检索结果 - Alice Lau
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Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics 由 Niels Brügger, Ricardo Miramontes, Jie Wu, Ravinder Gulia, Madhu Sudhana Saddala, Alice Lau, Tam Quach, John C. Reidling, Vivek Swarup, Albert R. La Spada, Ryan G. Lim, Leslie M. Thompson
出版 2025Artigo -
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Methylene Blue Modulates Huntingtin Aggregation Intermediates and Is Protective in Huntington's Disease Models 由 Emily M. Sontag, Gregor P. Lotz, Namita Agrawal, Andrew Tran, Rebecca Aron, Guocheng Yang, Mihaela Necula, Alice Lau, Steven Finkbeiner, Charles Glabe, J. Lawrence Marsh, Paul J. Muchowski, Leslie M. Thompson
出版 2012Artigo -
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Serine 421 regulates mutant huntingtin toxicity and clearance in mice 由 Ian H. Kratter, Hengameh Zahed, Alice Lau, Andrey S. Tsvetkov, Aaron Daub, Kurt F. Weiberth, Xiaofeng Gu, Frédéric Saudou, Sandrine Humbert, X. William Yang, Alex Osmand, Joan S. Steffan, Eliezer Masliah, Steven Finkbeiner
出版 2016Artigo -
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TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease 由 Xiaobei Zhao, Xu‐Qiao Chen, Eugene Kiwo Han, Yue Hu, Paul K. Paik, Zhiyong Ding, Julia Overman, Alice Lau, Sarah H. Shahmoradian, Wah Chiu, Leslie M. Thompson, Chengbiao Wu, William C. Mobley
出版 2016Artigo -
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Potential function for the Huntingtin protein as a scaffold for selective autophagy 由 Joseph Ochaba, Tamás Lukácsovich, George Csikós, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice Lau, Sylvia Y. Yeung, Sandrine Humbert, Frédéric Saudou, Daniel J. Klionsky, Steven Finkbeiner, Scott Zeitlin, J. Lawrence Marsh, David E. Housman, Leslie M. Thompson, Joan S. Steffan
出版 2014Artigo -
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Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease 由 Haiqun Jia, Judit Pallos, Vincent Jacques, Alice Lau, Bin Tang, Andrew C. Cooper, Adeela Syed, Judith Purcell, Yi Chen, Shefali Sharma, Gavin R. Sangrey, Shayna B. Darnell, Heather L. Plasterer, Ghazaleh Sadri‐Vakili, Joel Gottesfeld, Leslie M. Thompson, James R. Rusche, J. Lawrence Marsh, Elizabeth A. Thomas
出版 2012Artigo -
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Huntington’s disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization 由 Isabella Sanchez, Thai B. Nguyen, Whitney England, Ryan G. Lim, Anthony Q. Vu, Ricardo Miramontes, Lauren M. Byrne, Sebastian Markmiller, Alice Lau, Iliana Orellana, Maurice A. Curtis, Richard Lewis Maxwell Faull, G Yeo, Christie D. Fowler, Jack C. Reidling, Edward J. Wild, Robert C. Spitale, Leslie M. Thompson
出版 2021Artigo -
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Targeting H3K4 trimethylation in Huntington disease 由 Malini Vashishtha, Christopher Ng, Ferah Yildirim, Theresa A. Gipson, Ian H. Kratter, László Bodai, Wan Song, Alice Lau, Adam Labadorf, Annie Vogel Ciernia, Juan C. Troncosco, Christopher A. Ross, Gillian P. Bates, Dimitri Krainc, Ghazaleh Sadri‐Vakili, Steven Finkbeiner, J. Lawrence Marsh, David E. Housman, Ernest Fraenkel, Leslie M. Thompson
出版 2013Artigo -
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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome 由 Leslie M. Thompson, Charity T. Aiken, Linda S. Kaltenbach, Namita Agrawal, Katalin Illes, Ali Khoshnan, Marta Martínez‐Vicente, Montserrat Arrasate, Jacqueline G. O’Rourke, Hasan Khashwji, Tamás Lukácsovich, Yazhen Zhu, Alice Lau, Ashish C. Massey, Michael R. Hayden, Scott Zeitlin, Steven Finkbeiner, Kim N. Green, Frank M. LaFerla, Gillian P. Bates, Lan Huang, Paul H. Patterson, Donald C. Lo, Ana María Cuervo, J. Lawrence Marsh, Joan S. Steffan
出版 2009Artigo -
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Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice 由 Jack C. Reidling, Aroa Relaño-Ginés, Sandra M. Holley, Joseph Ochaba, Cindy Moore, Brian Fury, Alice Lau, Andrew Tran, Sylvia Y. Yeung, Delaram Salamati, Chunni Zhu, Asa Hatami, Carlos Cepeda, Joshua Barry, Talia Kamdjou, Alvin R. King, Dane Coleal‐Bergum, Nicholas R. Franich, Frank M. LaFerla, Joan S. Steffan, Mathew Blurton‐Jones, Charles K. Meshul, Gerhard Bauer, Michael S. Levine, Marie-Françoise Chesselet, Leslie M. Thompson
出版 2017Artigo -
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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation 由 Ryan G. Lim, Osama Al‐Dalahmah, Jie Wu, Maxwell P. Gold, Jack C. Reidling, Guomei Tang, Miriam Adam, David K. Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M. Reyes-Ortiz, Alice Lau, Richard A. Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette R. McClure, Xena Flowers, Jean Paul Vonsattel, Shawn M. Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E. Goldman, Leslie M. Thompson
出版 2022Artigo -
20
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease 由 Eva L. Morozko, Charlene Smith-Geater, Alejandro Mas Monteys, Subrata Pradhan, Ryan G. Lim, Peter Langfelder, Marketta Kachemov, Jayesh A. Kulkarni, Josh Zaifman, Austin Hill, Jennifer Stocksdale, Pieter R. Cullis, Jie Wu, Joseph Ochaba, Ricardo Miramontes, Anirban Chakraborty, Tapas K. Hazra, Alice Lau, Sophie St-Cyr, Iliana Orellana, Lexi Kopan, Keona Q. Wang, Sylvia Y. Yeung, Blair R. Leavitt, Jack C. Reidling, X. William Yang, Joan S. Steffan, Beverly L. Davidson, Partha Sarathi Sarkar, Leslie M. Thompson
出版 2021Artigo
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