Search Results - Alexander Penson

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  1. 1
    Unifying cancer and normal RNA sequencing data from different sources

    Unifying cancer and normal RNA sequencing data from different sources by Qingguo Wang, Joshua Armenia, Chao Zhang, Alexander Penson, Ed Reznik, Liguo Zhang, Thais Minet, Angelica Ochoa, Benjamin Groß, Christine A. Iacobuzio‐Donahue, Doron Betel, Barry S. Taylor, Jianjiong Gao, Nikolaus Schultz

    Published 2018
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  2. 2
    Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms

    Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms by Justin Taylor, Xiaoli Mi, Khrystyna North, Moritz Binder, Alexander Penson, Terra L. Lasho, Katherine Knorr, Michael Haddadin, Bo Liu, Joseph Pangallo, Salima Benbarche, Daniel H. Wiseman, Ayalew Tefferi, Stephanie Halene, Yang Liang, Mrinal M. Patnaik, Robert K. Bradley, Omar Abdel‐Wahab

    Published 2020
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  3. 3
    Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes

    Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes by Michael Offin, Joseph M. Chan, Megan Tenet, Hira Rizvi, Ronglai Shen, Gregory J. Riely, Natasha Rekhtman, Yahya Daneshbod, Álvaro Quintanal-Villalonga, Alexander Penson, Matthew D. Hellmann, Maria E. Arcila, Marc Ladanyi, Dana Pe’er, Mark G. Kris, Charles M. Rudin, Helena A. Yu

    Published 2019
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  4. 4
    Phase and context shape the function of composite oncogenic mutations

    Phase and context shape the function of composite oncogenic mutations by Alexander N. Gorelick, Francisco J. Sánchez‐Rivera, Yanyan Cai, Craig M. Bielski, Evan Biederstedt, Philip Jonsson, Allison L. Richards, Neil Vasan, Alexander Penson, Noah D. Friedman, Yu-Jui Ho, Timour Baslan, Chaitanya Bandlamudi, Maurizio Scaltriti, Nikolaus Schultz, Scott W. Lowe, Ed Reznik, Barry S. Taylor

    Published 2020
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  5. 5
    Genome doubling shapes the evolution and prognosis of advanced cancers

    Genome doubling shapes the evolution and prognosis of advanced cancers by Craig M. Bielski, Ahmet Zehir, Alexander Penson, Mark T.A. Donoghue, Walid K. Chatila, Joshua Armenia, Matthew T. Chang, Alison M. Schram, Philip Jonsson, Chaitanya Bandlamudi, Pedram Razavi, Gopa Iyer, Mark E. Robson, Zsofia K. Stadler, Nikolaus Schultz, José Baselga, David B. Solit, David M. Hyman, Michael F. Berger, Barry S. Taylor

    Published 2018
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  6. 6
    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer

    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer by Craig M. Bielski, Mark T.A. Donoghue, Mayur Gadiya, Aphrothiti J. Hanrahan, Helen Won, Matthew T. Chang, Philip Jonsson, Alexander Penson, Alexander N. Gorelick, Christopher Harris, Alison M. Schram, Aijazuddin Syed, Ahmet Zehir, Paul B. Chapman, David M. Hyman, David B. Solit, Kevin Shannon, Sarat Chandarlapaty, Michael F. Berger, Barry S. Taylor

    Published 2018
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  7. 7
    Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis

    Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis by Matthew T. Chang, Alexander Penson, Neil B. Desai, Nicholas D. Socci, Ronglai Shen, Venkatraman Seshan, Ritika Kundra, Adam Abeshouse, Agnès Viale, K. Eugene, Xueli Hao, Victor E. Reuter, Charles M. Rudin, Bernard H. Bochner, Jonathan E. Rosenberg, Dean F. Bajorin, Nikolaus Schultz, Michael F. Berger, Gopa Iyer, David B. Solit, Hikmat Al‐Ahmadie, Barry S. Taylor

    Published 2017
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  8. 8
    Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care

    Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care by Alexander Penson, Niedzica Camacho, Youyun Zheng, Anna M. Varghese, Hikmat Al‐Ahmadie, Pedram Razavi, Sarat Chandarlapaty, Christina Vallejo, Efsevia Vakiani, Teresa Gilewski, Jonathan E. Rosenberg, Maha Shady, Dana W.Y. Tsui, Dalicia N. Reales, Adam Abeshouse, Aijazuddin Syed, Ahmet Zehir, Nikolaus Schultz, Marc Ladanyi, David B. Solit, David S. Klimstra, David M. Hyman, Barry S. Taylor, Michael F. Berger

    Published 2019
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  9. 9
    The Evolutionary Origins of Recurrent Pancreatic Cancer

    The Evolutionary Origins of Recurrent Pancreatic Cancer by Hitomi Sakamoto, Marc A. Attiyeh, Jeffrey M. Gerold, Alvin Makohon‐Moore, Akimasa Hayashi, Jungeui Hong, Rajya Kappagantula, Lance Zhang, Jerry P. Melchor, Johannes G. Reiter, Alexander Heyde, Craig M. Bielski, Alexander Penson, Mithat Gönen, Debyani Chakravarty, Eileen M. O’Reilly, Laura D. Wood, Ralph H. Hruban, Martin A. Nowak, Nicholas D. Socci, Barry S. Taylor, Christine A. Iacobuzio‐Donahue

    Published 2020
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  10. 10
    Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

    Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis by Justin Taylor, Maria Sendino, Alexander N. Gorelick, Alessandro Pastore, Matthew T. Chang, Alexander Penson, Elena I. Gavrila, Connor Stewart, Ella M. Melnik, Florisela Herrejon Chavez, Lillian Bitner, Akihide Yoshimi, Stanley Chun-Wei Lee, Daichi Inoue, Bo Liu, Xiao J. Zhang, Anthony R. Mato, Ahmet Doǧan, Michael G. Kharas, Yuhong Chen, Demin Wang, Rajesh K. Soni, Ronald C. Hendrickson, Gorka Prieto, José Antonio Rodríguez, Barry S. Taylor, Omar Abdel‐Wahab

    Published 2019
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  11. 11
    Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia

    Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia by Eric Wang, Jose Mario Bello Pineda, Won Jun Kim, Sisi Chen, Jessie Bourcier, Maximilian Stahl, Simon J. Hogg, Jan Phillipp Bewersdorf, Cuijuan Han, Michael Singer, Daniel Cui, Caroline Erickson, Steven Tittley, Alexander Penson, Katherine Knorr, Robert Stanley, Jahan Rahman, Gnana P. Krishnamoorthy, James A. Fagin, Emily Creger, Elizabeth A. McMillan, Chi‐Ching Mak, Matthew C. Jarvis, Carine Bossard, Darrin M. Beaupre, Robert K. Bradley, Omar Abdel‐Wahab

    Published 2022
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  12. 12
    Accelerating Discovery of Functional Mutant Alleles in Cancer

    Accelerating Discovery of Functional Mutant Alleles in Cancer by Matthew T. Chang, Tripti Shrestha Bhattarai, Alison M. Schram, Craig M. Bielski, Mark T.A. Donoghue, Philip Jonsson, Debyani Chakravarty, Sarah Phillips, Cyriac Kandoth, Alexander Penson, Alexander N. Gorelick, Tambudzai Shamu, Swati Patel, Christopher Harris, Jianjiong Gao, S. Onur Sumer, Ritika Kundra, Pedram Razavi, Bob T. Li, Dalicia N. Reales, Nicholas D. Socci, Gowtham Jayakumaran, Ahmet Zehir, Ryma Benayed, Maria E. Arcila, Sarat Chandarlapaty, Marc Ladanyi, Nikolaus Schultz, José Baselga, Michael F. Berger, Neal Rosen, David B. Solit, David M. Hyman, Barry S. Taylor

    Published 2017
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  13. 13
    The context-specific role of germline pathogenicity in tumorigenesis

    The context-specific role of germline pathogenicity in tumorigenesis by Preethi Srinivasan, Chaitanya Bandlamudi, Philip Jonsson, Yelena Kemel, Shweta S. Chavan, Allison L. Richards, Alexander Penson, Craig M. Bielski, Christopher J. Fong, Aijazuddin Syed, Gowtham Jayakumaran, Meera Prasad, Jason Hwee, S. Onur Sumer, Ino de Bruijn, Xiang Li, Jianjiong Gao, Nikolaus Schultz, Roy Cambria, Jesse Galle, Semanti Mukherjee, Joseph Vijai, Karen A. Cadoo, Maria I. Carlo, Michael F. Walsh, Diana Mandelker, Ozge Ceyhan‐Birsoy, Jinru Shia, Ahmet Zehir, Marc Ladanyi, David M. Hyman, Liying Zhang, Kenneth Offit, Mark E. Robson, David B. Solit, Zsofia K. Stadler, Michael F. Berger, Barry S. Taylor

    Published 2021
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  14. 14
    Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making

    Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making by Wassim Abida, Joshua Armenia, Anuradha Gopalan, Ryan Brennan, Michael F. Walsh, David Barron, Daniel C. Danila, Dana E. Rathkopf, Michael J. Morris, Susan F. Slovin, Brigit McLaughlin, Kristen Curtis, David M. Hyman, Jeremy C. Durack, Stephen B. Solomon, Maria E. Arcila, Ahmet Zehir, Aijazuddin Syed, Jianjiong Gao, Debyani Chakravarty, Hebert Alberto Vargas, Mark E. Robson, Joseph Vijai, Kenneth Offit, Mark T.A. Donoghue, Adam Abeshouse, Ritika Kundra, Zachary Heins, Alexander Penson, Christopher Harris, Barry S. Taylor, Marc Ladanyi, Diana Mandelker, Liying Zhang, Victor E. Reuter, Philip W. Kantoff, David B. Solit, Michael F. Berger, Charles L. Sawyers, Nikolaus Schultz, Howard I. Scher

    Published 2017
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  15. 15
    The long tail of oncogenic drivers in prostate cancer

    The long tail of oncogenic drivers in prostate cancer by Joshua Armenia, Stephanie A. Wankowicz, David Liu, Jianjiong Gao, Ritika Kundra, Ed Reznik, Walid K. Chatila, Debyani Chakravarty, G. Celine Han, Ilsa M. Coleman, Bruce Montgomery, Colin C. Pritchard, Colm Morrissey, Christopher E. Barbieri, Himisha Beltran, Andrea Sboner, Zafeiris Zafeiriou, Susana Miranda, Craig M. Bielski, Alexander Penson, Charlotte Tolonen, Franklin W. Huang, Dan R. Robinson, Yi Mi Wu, Robert J. Lonigro, Levi A. Garraway, Francesca Demichelis, Philip W. Kantoff, Mary‐Ellen Taplin, Wassim Abida, Barry S. Taylor, Howard I. Scher, Peter S. Nelson, Johann S. de Bono, Mark A. Rubin, Charles L. Sawyers, Arul M. Chinnaiyan, Nikolaus Schultz, Eliezer M. Van Allen

    Published 2018
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  16. 16
    The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers

    The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers by Pedram Razavi, Matthew T. Chang, Guotai Xu, Chaitanya Bandlamudi, Dara S. Ross, Neil Vasan, Yanyan Cai, Craig M. Bielski, Mark T.A. Donoghue, Philip Jonsson, Alexander Penson, Ronglai Shen, Fresia Pareja, Ritika Kundra, Sumit Middha, Michael L. Cheng, Ahmet Zehir, Cyriac Kandoth, Ruchi Patel, Kety Huberman, Lillian M. Smyth, Komal Jhaveri, Shanu Modi, Tiffany A. Traina, Chau T. Dang, Wen Zhang, Britta Weigelt, Bob T. Li, Marc Ladanyi, David M. Hyman, Nikolaus Schultz, Mark E. Robson, Clifford A. Hudis, Edi Brogi, Agnès Viale, Larry Norton, Maura N. Dickler, Michael F. Berger, Christine A. Iacobuzio‐Donahue, Sarat Chandarlapaty, Maurizio Scaltriti, Jorge S. Reis‐Filho, David B. Solit, Barry S. Taylor, José Baselga

    Published 2018
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  17. 17
    Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma by A. Gordon Robertson, Juliann Shih, Christina Yau, Ewan A. Gibb, Junna Oba, Karen Mungall, Julian M. Hess, Vladislav Uzunangelov, Vonn Walter, Ludmila Danilova, Tara M. Lichtenberg, Melanie H. Kucherlapati, Patrick K. Kimes, Ming Tang, Alexander Penson, Özgün Babur, Rehan Akbani, Christopher A. Bristow, Katherine A. Hoadley, Lisa Iype, Matthew T. Chang, Andrew D. Cherniack, Christopher C. Benz, Gordon B. Mills, Roel G.W. Verhaak, Klaus Griewank, Ina Felau, Jean C. Zenklusen, Hui Shen, Lynn Schoenfield, Alexander J. Lazar, Mohamed H. Abdel‐Rahman, Sergio Román-Román, Marc‐Henri Stern, Colleen M. Cebulla, Michelle D. Williams, Martine J. Jager, Sarah E. Coupland, Bita Esmaeli, Cyriac Kandoth, Scott E. Woodman

    Published 2018
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  18. 18
    A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia

    A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia by John Mascarenhas, Heidi E. Kosiorek, Josef T. Prchal, Alessandro Rambaldi, Dmitriy Berenzon, Abdulraheem Yacoub, Claire Harrison, Mary Frances McMullin, Alessandro M. Vannucchi, Joanne Ewing, Casey L. O’Connell, Jean‐Jacques Kiladjian, Adam J. Mead, Elliott F. Winton, D Leibowitz, Valerio De Stefano, Murat O. Arcasoy, Craig M. Kessler, Rosalind Catchatourian, Damiano Rondelli, Richard T. Silver, Andrea Bacigalupo, Arnon Nagler, Marina Kremyanskaya, Max F. Levine, Juan Arango Ossa, Erin McGovern, Lonette Sandy, Mohamad E. Salama, Vesna Najfeld, Joseph Tripodi, Noushin Farnoud, Alexander Penson, Rona Singer Weinberg, Leah Price, Judith D. Goldberg, Tiziano Barbui, Roberto Marchioli, Gianni Tognoni, Raajit K. Rampal, Ruben A. Mesa, Amylou C. Dueck, Ronald Hoffman

    Published 2022
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  19. 19
    Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer

    Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer by Alicia Latham, Preethi Srinivasan, Yelena Kemel, Jinru Shia, Chaitanya Bandlamudi, Diana Mandelker, Sumit Middha, Jaclyn F. Hechtman, Ahmet Zehir, Marianne Dubard-Gault, Christina Tran, Carolyn Stewart, Margaret Sheehan, Alexander Penson, Deborah F. DeLair, Rona Yaeger, Joseph Vijai, Semanti Mukherjee, Jesse Galle, Mark A. Dickson, Yelena Y. Janjigian, Eileen M. O’Reilly, Neil H. Segal, Leonard B. Saltz, Diane Reidy‐Lagunes, Anna M. Varghese, Dean F. Bajorin, Maria I. Carlo, Karen A. Cadoo, Michael F. Walsh, Martin R. Weiser, Julio García Aguilar, David S. Klimstra, Luis A. Díaz, José Baselga, Liying Zhang, Marc Ladanyi, David M. Hyman, David B. Solit, Mark E. Robson, Barry S. Taylor, Kenneth Offit, Michael F. Berger, Zsofia K. Stadler

    Published 2018
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  20. 20
    Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

    Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients by Ahmet Zehir, Ryma Benayed, Ronak Shah, Aijazuddin Syed, Sumit Middha, Hyunjae R. Kim, Preethi Srinivasan, Jianjiong Gao, Debyani Chakravarty, Sean M. Devlin, Matthew D. Hellmann, David Barron, Alison M. Schram, Meera Hameed, Snjezana Doğan, Dara S. Ross, Jaclyn F. Hechtman, Deborah F. DeLair, JinJuan Yao, Diana Mandelker, Donavan T. Cheng, Raghu Chandramohan, Abhinita Mohanty, Ryan Ptashkin, Gowtham Jayakumaran, Meera Prasad, Mustafa Syed, Anoop Balakrishnan Rema, Zhen Y. Liu, Khédoudja Nafa, Laetitia Borsu, Justyna Sadowska, Jacklyn Casanova, Ruben Bacares, Iwona Kiecka, Anna Razumova, Julie B Son, Lisa Stewart, Tessara Baldi, Kerry Mullaney, Hikmat Al‐Ahmadie, Efsevia Vakiani, Adam Abeshouse, Alexander Penson, Philip Jonsson, Niedzica Camacho, Matthew T. Chang, Helen Won, Benjamin Groß, Ritika Kundra, Zachary Heins, Hsiao‐Wei Chen, Sarah Phillips, Hongxin Zhang, Jiaojiao Wang, Angelica Ochoa, Jonathan Wills, Michael Eubank, Stacy B. Thomas, Stuart M. Gardos, Dalicia N. Reales, Jesse Galle, Robert Durany, Roy Cambria, Wassim Abida, Andrea Cercek, Darren R. Feldman, Mrinal M. Gounder, A. Ari Hakimi, James J. Harding, Gopa Iyer, Yelena Y. Janjigian, Emmet Jordan, Ciara M. Kelly, Maeve A. Lowery, Luc G.T. Morris, Antonio Omuro, Nitya Raj, Pedram Razavi, Alexander N. Shoushtari, Neerav Shukla, Tara E. Soumerai, Anna M. Varghese, Rona Yaeger, Jonathan Coleman, Bernard H. Bochner, Gregory J. Riely, Leonard B. Saltz, Howard I. Scher, Paul Sabbatini, Mark E. Robson, David S. Klimstra, Barry S. Taylor, José Baselga, Nikolaus Schultz, David M. Hyman, Maria E. Arcila, David B. Solit, Marc Ladanyi, Michael F. Berger

    Published 2017
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