检索结果 - Alexander N. Gorelick

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  1. 1
    Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA

    Respiratory complex and tissue lineage drive recurrent mutations in tumour mtDNA 由 Alexander N. Gorelick, Minsoo Kim, Walid K. Chatila, Konnor La, A. Ari Hakimi, Michael F. Berger, Barry S. Taylor, Payam A. Gammage, Ed Reznik

    出版 2021
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  2. 2
    V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer

    V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer 由 Yijun Gao, Ann Maria, Na Na, Arnaud Da Cruz Paula, Alexander N. Gorelick, Jaclyn F. Hechtman, Julianne Carson, Robert A. Lefkowitz, Britta Weigelt, Barry S. Taylor, HuiYong Zhao, Jorge S. Reis‐Filho, Elisa de Stanchina, Neal Rosen, Zhan Yao, Rona Yaeger

    出版 2019
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  3. 3
    Phase and context shape the function of composite oncogenic mutations

    Phase and context shape the function of composite oncogenic mutations 由 Alexander N. Gorelick, Francisco J. Sánchez‐Rivera, Yanyan Cai, Craig M. Bielski, Evan Biederstedt, Philip Jonsson, Allison L. Richards, Neil Vasan, Alexander Penson, Noah D. Friedman, Yu-Jui Ho, Timour Baslan, Chaitanya Bandlamudi, Maurizio Scaltriti, Nikolaus Schultz, Scott W. Lowe, Ed Reznik, Barry S. Taylor

    出版 2020
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  4. 4
    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer

    Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer 由 Craig M. Bielski, Mark T.A. Donoghue, Mayur Gadiya, Aphrothiti J. Hanrahan, Helen Won, Matthew T. Chang, Philip Jonsson, Alexander Penson, Alexander N. Gorelick, Christopher Harris, Alison M. Schram, Aijazuddin Syed, Ahmet Zehir, Paul B. Chapman, David M. Hyman, David B. Solit, Kevin Shannon, Sarat Chandarlapaty, Michael F. Berger, Barry S. Taylor

    出版 2018
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  5. 5
    Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes

    Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes 由 Minsoo Kim, Alexander N. Gorelick, Ignacio Vázquez-Garćıa, Marc Williams, Sohrab Salehi, Hongyu Shi, Adam C. Weiner, Nick Ceglia, Tyler Funnell, Tricia Park, Sonia Boscenco, Ciara H. O’Flanagan, Hui Jiang, Diljot Grewal, Cerise Tang, Nicole Rusk, Payam A. Gammage, Andrew McPherson, Samuel Aparício, Sohrab P. Shah, Ed Reznik

    出版 2024
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  6. 6
    Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course

    Putative Drivers of Aggressiveness in TCEB1-mutant Renal Cell Carcinoma: An Emerging Entity with Variable Clinical Course 由 Renzo G. DiNatale, Alexander N. Gorelick, Vladimir Makarov, Kyle A. Blum, Andrew W. Silagy, Benjamin Freeman, Diego Chowell, Julian Marcon, Roy Mano, Álex Sánchez‐Pla, Kyrollis Attalla, Stanley Weng, Martin H. Voss, Robert J. Motzer, Paul Russo, Jonathan Coleman, Victor E. Reuter, Ying‐Bei Chen, Timothy A. Chan, Ed Reznik, Satish K. Tickoo, A. Ari Hakimi

    出版 2019
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  7. 7
    Quantifying cell divisions along evolutionary lineages in cancer

    Quantifying cell divisions along evolutionary lineages in cancer 由 Martin Blohmer, David Cheek, Wei‐Ting Hung, M. A. Kessler, Foivos Chatzidimitriou, Jiahe Wang, William W. Hung, I‐Hsiu Lee, Alexander N. Gorelick, Emma C. E. Wassenaar, Ching-Yeuh Yang, Yi‐Chen Yeh, Hsiang‐Ling Ho, Dorothee Speiser, Maria Margarete Karsten, Michael Lanuti, Sara I. Pai, Onno Kranenburg, Jochen K. Lennerz, Teh-Ying Chou, Matthias Kloor, Kamila Naxerova

    出版 2025
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  8. 8
    Double <i>PIK3CA</i> mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

    Double <i>PIK3CA</i> mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors 由 Neil Vasan, Pedram Razavi, Jared L. Johnson, Hong Shao, Hardik Shah, Alesia Antoine, Erik Ladewig, Alexander N. Gorelick, Ting-Yu Lin, Eneda Toska, Guotai Xu, Abiha Kazmi, Matthew T. Chang, Barry S. Taylor, Maura N. Dickler, Komal Jhaveri, Sarat Chandarlapaty, Raúl Rabadán, Ed Reznik, Melissa Smith, Robert Sebra, Frauke Schimmöller, Timothy R. Wilson, Lori S. Friedman, Lewis C. Cantley, Maurizio Scaltriti, José Baselga

    出版 2019
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  9. 9
    Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis

    Altered Nuclear Export Signal Recognition as a Driver of Oncogenesis 由 Justin Taylor, Maria Sendino, Alexander N. Gorelick, Alessandro Pastore, Matthew T. Chang, Alexander Penson, Elena I. Gavrila, Connor Stewart, Ella M. Melnik, Florisela Herrejon Chavez, Lillian Bitner, Akihide Yoshimi, Stanley Chun-Wei Lee, Daichi Inoue, Bo Liu, Xiao J. Zhang, Anthony R. Mato, Ahmet Doǧan, Michael G. Kharas, Yuhong Chen, Demin Wang, Rajesh K. Soni, Ronald C. Hendrickson, Gorka Prieto, José Antonio Rodríguez, Barry S. Taylor, Omar Abdel‐Wahab

    出版 2019
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  10. 10
    TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors

    TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors 由 Emiliano Cocco, Ji Eun Lee, Srinivasaraghavan Kannan, Alison M. Schram, Helen Won, Sophie Shifman, Amanda Kulick, Laura Baldino, Eneda Toska, Amaia Arruabarrena-Aristorena, Srushti Kittane, Fan Wu, Yanyan Cai, Sabrina Arena, Benedetta Mussolin, Ram Kannan, Neil Vasan, Alexander N. Gorelick, Michael F. Berger, Ofra Novoplansky, Sankar Jagadeeshan, Yi Liao, Uwe Rix, Sandra Misale, Barry S. Taylor, Alberto Bardelli, Jaclyn F. Hechtman, David M. Hyman, Moshe Elkabets, Elisa de Stanchina, Chandra Verma, Andrea Ventura, Alexander Drilon, Maurizio Scaltriti

    出版 2020
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  11. 11
    Accelerating Discovery of Functional Mutant Alleles in Cancer

    Accelerating Discovery of Functional Mutant Alleles in Cancer 由 Matthew T. Chang, Tripti Shrestha Bhattarai, Alison M. Schram, Craig M. Bielski, Mark T.A. Donoghue, Philip Jonsson, Debyani Chakravarty, Sarah Phillips, Cyriac Kandoth, Alexander Penson, Alexander N. Gorelick, Tambudzai Shamu, Swati Patel, Christopher Harris, Jianjiong Gao, S. Onur Sumer, Ritika Kundra, Pedram Razavi, Bob T. Li, Dalicia N. Reales, Nicholas D. Socci, Gowtham Jayakumaran, Ahmet Zehir, Ryma Benayed, Maria E. Arcila, Sarat Chandarlapaty, Marc Ladanyi, Nikolaus Schultz, José Baselga, Michael F. Berger, Neal Rosen, David B. Solit, David M. Hyman, Barry S. Taylor

    出版 2017
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  12. 12
    Efficacy and Determinants of Response to HER Kinase Inhibition in<i>HER2</i>-Mutant Metastatic Breast Cancer

    Efficacy and Determinants of Response to HER Kinase Inhibition in<i>HER2</i>-Mutant Metastatic Breast Cancer 由 Lillian M. Smyth, Sarina A. Piha‐Paul, Helen Won, Alison M. Schram, Cristina Saura, Sherene Loi, Janice Lu, Geoffrey I. Shapiro, Dejan Juric, Ingrid A. Mayer, Carlos L. Arteaga, Macarena I. de la Fuente, Adam M. Brufksy, Iben Spanggaard, Morten Mau‐Sørensen, Mónica Arnedos, Víctor Moreno, Valentina Boni, Joohyuk Sohn, Lee S. Schwartzberg, Xavier González, Andrés Cervantes, François‐Clément Bidard, Alexander N. Gorelick, Richard B. Lanman, Rebecca J. Nagy, Gary A. Ulaner, Sarat Chandarlapaty, Komal Jhaveri, Elena I. Gavrila, Catherine Zimel, S. Duygu Selçuklu, Myra Melcer, Aliaksandra Samoila, Yanyan Cai, Maurizio Scaltriti, Grace Mann, Feng Xu, Lisa D. Eli, Melanie Dujka, Alshad S. Lalani, Richard Bryce, José Baselga, Barry S. Taylor, David B. Solit, Funda Meric‐Bernstam, David M. Hyman

    出版 2019
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