Risultati della ricerca - Alessandro Datti

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  1. 1
    MicroRNA Implications across Neurodevelopment and Neuropathology

    MicroRNA Implications across Neurodevelopment and Neuropathology di Sabata Martino, Ilaria di Girolamo, Antonio Orlacchio, Alessandro Datti, Aldo Orlacchio

    Pubblicazione 2009
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  2. 2
    High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer

    High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer di Julia Izrailit, Hal K. Berman, Alessandro Datti, Jeffrey L. Wrana, Michael Reedijk

    Pubblicazione 2013
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  3. 3
    Digitoxin-Induced Cytotoxicity in Cancer Cells Is Mediated through Distinct Kinase and Interferon Signaling Networks

    Digitoxin-Induced Cytotoxicity in Cancer Cells Is Mediated through Distinct Kinase and Interferon Signaling Networks di Ioannis Prassas, George S. Karagiannis, Ihor Batruch, Apostolos Dimitromanolakis, Alessandro Datti, Eleftherios P. Diamandis

    Pubblicazione 2011
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  4. 4
    Inhibition of Osteoclast Bone Resorption by Disrupting Vacuolar H+-ATPase a3-B2 Subunit Interaction

    Inhibition of Osteoclast Bone Resorption by Disrupting Vacuolar H+-ATPase a3-B2 Subunit Interaction di Norbert Kartner, Yeqi Yao, Keying Li, Gazelle Jean Crasto, Alessandro Datti, Morris F. Manolson

    Pubblicazione 2010
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  5. 5
    ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway

    ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway di Natalia Moskal, Victoria Riccio, Mikhail Bashkurov, Rediet Taddese, Alessandro Datti, Peter N. Lewis, G. Angus McQuibban

    Pubblicazione 2020
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  6. 6
    High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: Interaction with IQ motif-containing factors

    High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: Interaction with IQ motif-containing factors di Tyler Robinson, Melody Y. Pai, Jeff Liu, Frederick S. Vizeacoumar, Thomas Sun, Sean E. Egan, Alessandro Datti, Jing Huang, Eldad Zacksenhaus

    Pubblicazione 2013
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  7. 7
    Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

    Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming di Payman Samavarchi‐Tehrani, Azadeh Golipour, Laurent David, Hoon‐Ki Sung, Tobias A. Beyer, Alessandro Datti, Knut Woltjen, András Nagy, Jeffrey L. Wrana

    Pubblicazione 2010
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  8. 8
    RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs

    RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs di Tyler Robinson, Jeff C. Liu, Frederick S. Vizeacoumar, Thomas Sun, Neil MacLean, Sean E. Egan, Aaron D. Schimmer, Alessandro Datti, Eldad Zacksenhaus

    Pubblicazione 2013
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  9. 9
    Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells

    Small Molecule Kinase Inhibitor Screen Identifies Polo-Like Kinase 1 as a Target for Neuroblastoma Tumor-Initiating Cells di Natalie Grinshtein, Alessandro Datti, Mayumi Fujitani, David Uehling, Michaël Prakesch, Methvin Isaac, Meredith S. Irwin, Jeffrey L. Wrana, Rima Al‐awar, David R. Kaplan

    Pubblicazione 2011
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  10. 10
    Sorafenib as an Inhibitor of RUVBL2

    Sorafenib as an Inhibitor of RUVBL2 di Nardin Nano, Francisca Ugwu, Thiago Vargas Seraphim, Tangzhi Li, Gina Azer, Methvin Isaac, Michaël Prakesch, Leandro R.S. Barbosa, Carlos H.I. Ramos, Alessandro Datti, Walid A. Houry

    Pubblicazione 2020
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  11. 11
    Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain

    Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain di Brent D. G. Page, Steven Fletcher, Peibin Yue, Zhihua Li, Xiaolei Zhang, Sumaiya Sharmeen, Alessandro Datti, Jeffrey L. Wrana, Suzanne Trudel, Aaron D. Schimmer, James Turkson, Patrick T. Gunning

    Pubblicazione 2011
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  12. 12
    PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma

    PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma di Yael Babichev, Leah Kabaroff, Alessandro Datti, David Uehling, Methvin Isaac, Rima Al‐awar, Michaël Prakesch, Ren Sun, Paul C. Boutros, Rosemarie E. Venier, Brendan C. Dickson, Rebecca Gladdy

    Pubblicazione 2016
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  13. 13
    Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells

    Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells di Yanina Eberhard, Sean McDermott, Xiaoming Wang, Marcela Gronda, Amudha L. Venugopal, Tabitha E. Wood, Rose Hurren, Alessandro Datti, Robert A. Batey, Jeffrey L. Wrana, William E. Antholine, John E. Dick, Aaron D. Schimmer

    Pubblicazione 2009
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  14. 14
    Combined deletion of <scp>P</scp>ten and p53 in mammary epithelium accelerates triple‐negative breast cancer with dependency on e<scp>EF</scp>2<scp>K</scp>

    Combined deletion of <scp>P</scp>ten and p53 in mammary epithelium accelerates triple‐negative breast cancer with dependency on e<scp>EF</scp>2<scp>K</scp> di Jeff C. Liu, Véronique Voisin, Sharon Wang, Dong‐Yu Wang, Robert A. Jones, Alessandro Datti, David Uehling, Rima Al‐awar, Sean E. Egan, Gary D. Bader, Ming‐Sound Tsao, Tak W. Mak, Eldad Zacksenhaus

    Pubblicazione 2014
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  15. 15
    Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation

    Inhibition of the Sodium Potassium Adenosine Triphosphatase Pump Sensitizes Cancer Cells to Anoikis and Prevents Distant Tumor Formation di Craig D. Simpson, Imtiaz A. Mawji, Kika Anyiwe, Moyo A. Williams, Xiaoming Wang, Amudha L. Venugopal, Marcela Gronda, Rose Hurren, Sonia Cheng, Stefano Serra, Reza Beheshti Zavareh, Alessandro Datti, Jeffrey L. Wrana, Shereen Ezzat, Aaron D. Schimmer

    Pubblicazione 2009
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  16. 16
    Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis

    Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis di Franco J. Vizeacoumar, Nydia van Dyk, Frederick S. Vizeacoumar, Vincent C. K. Cheung, Jingjing Li, Yaroslav Sydorskyy, Nicolle Case, Zhijian Li, Alessandro Datti, Corey Nislow, Brian Raught, Zhaolei Zhang, Brendan J. Frey, Kerry Bloom, Charles Boone, Brenda Andrews

    Pubblicazione 2010
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  17. 17
    The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

    The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells di Sumaiya Sharmeen, Marko Škrtić, Mahadeo A. Sukhai, Rose Hurren, Marcela Gronda, Xiaoming Wang, Sonali B. Fonseca, Hongxiang Sun, Tabitha E. Wood, Richard A. Ward, Mark D. Minden, Robert A. Batey, Alessandro Datti, Jeffrey L. Wrana, Shana O. Kelley, Aaron D. Schimmer

    Pubblicazione 2010
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  18. 18
    Selective targeting of neuroblastoma tumour‐initiating cells by compounds identified in stem cell‐based small molecule screens

    Selective targeting of neuroblastoma tumour‐initiating cells by compounds identified in stem cell‐based small molecule screens di Kristen M. Smith, Alessandro Datti, Mayumi Fujitani, Natalie Grinshtein, Libo Zhang, Olena Morozova, Kim M. Blakely, Susan A. Rotenberg, Loen M. Hansford, Freda D. Miller, Herman Yeger, Meredith S. Irwin, Jason Moffat, Marco A. Marra, Sylvain Baruchel, Jeffrey L. Wrana, David R. Kaplan

    Pubblicazione 2010
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  19. 19
    Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

    Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma di Xueqing Lun, J. Connor Wells, Natalie Grinshtein, Jennifer C. King, Xiaoguang Hao, Ngoc-Ha Dang, Xiuling Wang, Ahmed Aman, David Uehling, Alessandro Datti, Jeffrey L. Wrana, Jacob C. Easaw, Artee Luchman, Samuel Weiss, J. Gregory Cairncross, David R. Kaplan, Stephen M. Robbins, Donna L. Senger

    Pubblicazione 2016
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  20. 20
    RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation

    RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation di Robert A. Jones, Tyler Robinson, Jeff C. Liu, Mariusz Shrestha, Véronique Voisin, YoungJun Ju, Philip E.D. Chung, Giovanna Pellecchia, Victoria L. Fell, Sooin Bae, Lakshmi Muthuswamy, Alessandro Datti, Sean E. Egan, Zhe Jiang, Gustavo Leone, Gary D. Bader, Aaron D. Schimmer, Eldad Zacksenhaus

    Pubblicazione 2016
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