Rezultati - Alejandro Rojas‐Fernández

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  1. 1
    Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9

    Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9 od Alejandro Rojas‐Fernández, Lina Herhaus, Thomas Macartney, Christophe Lachaud, Ronald T. Hay, Gopal P. Sapkota

    Izdano 2015
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  2. 2
    SUMO Chain-Induced Dimerization Activates RNF4

    SUMO Chain-Induced Dimerization Activates RNF4 od Alejandro Rojas‐Fernández, Anna Plechanovová, Neil Hattersley, Ellis Jaffray, Michael H. Tatham, Ronald T. Hay

    Izdano 2014
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  3. 3
    The Potential Role of SARS-COV-2 in the Pathogenesis of Parkinson's Disease

    The Potential Role of SARS-COV-2 in the Pathogenesis of Parkinson's Disease od Pedro Chaná‐Cuevas, Philippe Salles-Gándara, Alejandro Rojas‐Fernández, Constanza Salinas-Rebolledo, Anna Milán

    Izdano 2020
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  4. 4
    An affinity-directed protein missile system for targeted proteolysis

    An affinity-directed protein missile system for targeted proteolysis od Luke J. Fulcher, Thomas Macartney, Polyxeni Bozatzi, Annika Hornberger, Alejandro Rojas‐Fernández, Gopal P. Sapkota

    Izdano 2016
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  5. 5
    The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

    The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA od Ellis Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmańska, Alejandro Rojas‐Fernández, Yili Yin, Graeme Ball, Ronald T. Hay

    Izdano 2023
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  6. 6
    DHX15 regulates CMTR1-dependent gene expression and cell proliferation

    DHX15 regulates CMTR1-dependent gene expression and cell proliferation od Francisco Inesta‐Vaquera, Viduth K. Chaugule, Alison Galloway, Laurel C. Chandler, Alejandro Rojas‐Fernández, Simone Weidlich, Mark Peggie, Victoria H. Cowling

    Izdano 2018
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  7. 7
    PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways

    PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways od Ellis Jaffray, Michael H. Tatham, Barbara Mojsa, Anna Plechanovová, Alejandro Rojas‐Fernández, Julio C.Y. Liu, Niels Mailand, Adel F.M. Ibrahim, Graeme Ball, Iain M. Porter, Ronald T. Hay

    Izdano 2025
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  8. 8
    Autophagosomes cooperate in the degradation of intracellular C‐terminal fragments of the amyloid precursor protein <i>via</i> the MVB/lysosomal pathway

    Autophagosomes cooperate in the degradation of intracellular C‐terminal fragments of the amyloid precursor protein <i>via</i> the MVB/lysosomal pathway od Alexis González, Vanessa C. Muñoz, Viviana A. Cavieres, Hianara A. Bustamante, Víctor Hugo Cornejo, Yunan C. Januário, Ibeth González, Claudio Hetz, Luis LP da Silva, Alejandro Rojas‐Fernández, Ronald T. Hay, Gonzalo A. Mardones, Patricia V. Burgos

    Izdano 2017
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  9. 9
    Distinct roles of ascorbic acid in extracellular vesicles and free form: Implications for metabolism and oxidative stress in presymptomatic Huntington's Disease

    Distinct roles of ascorbic acid in extracellular vesicles and free form: Implications for metabolism and oxidative stress in presymptomatic Huntington's Disease od Felipe Beltrán, Leandro Torres-Díaz L, Paulina Troncoso-Escudero, Juan Villalobos-González, Gonzalo A. Mayorga-Weber, Marcelo Lara, Adriana Covarrubias‐Pinto, Sharin Valdivia, Isidora Vicencio, Eduardo Papic, Carolina Paredes-Martínez, Mara E. da Silva-Januário, Alejandro Rojas‐Fernández, Luis L. P. daSilva, Felipe A. Court, Abraham Rosas‐Arellano, Luis Federico Bátiz, Patricio Rojas, Francisco J. Rivera, Maite A. Castro

    Izdano 2024
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  10. 10
    Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody

    Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody od G Valenzuela, Ronald Jara, Daniel Watterson, Naphak Modhiran, Alberto A. Amarilla, Johanna Himelreichs, Alexander A. Khromykh, Constanza Salinas-Rebolledo, Teresa Pinto, Yorka Cheuquemilla, Yago Margolles, Natalia López‐González del Rey, Zaray Miranda-Chacón, Alexei Cuevas, Anne Berking, Camila Deride, Sebastián González-Moraga, Héctor Mancilla, Daniel Maturana, Andreas Langer, Juan Pablo Toledo, Ananda Müller, Benjamín Uberti, Paola Krall, Pamela Ehrenfeld, Javier Blesa, Pedro Chaná‐Cuevas, Germán Rehren, David Schwefel, Luis Ángel Fernández, Alejandro Rojas‐Fernández

    Izdano 2021
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  11. 11
    Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

    Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology od Julio Aguado, Alberto A. Amarilla, Atefeh Taherian Fard, Eduardo A. Albornoz, Alexander Tyshkovskiy, Marius Schwabenland, Harman Kaur Chaggar, Naphak Modhiran, Cecilia Gómez‐Inclán, Ibrahim Javed, Alireza A. Baradar, Benjamin Liang, Lianli Peng, Malindrie Dharmaratne, Giovanni Pietrogrande, Pranesh Padmanabhan, Morgan E. Freney, Rhys Parry, Julian D. J. Sng, Ariel Isaacs, Alexander A. Khromykh, G Valenzuela, Alejandro Rojas‐Fernández, Thomas P. Davis, Marco Prinz, Bertram Bengsch, Vadim N. Gladyshev, Trent M. Woodruff, Jessica C. Mar, Daniel Watterson, Ernst J. Wolvetang

    Izdano 2023
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  12. 12
    SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

    SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein od Eduardo A. Albornoz, Alberto A. Amarilla, Naphak Modhiran, Sandra E. Parker, Xaria X. Li, Danushka K. Wijesundara, Julio Aguado, Adriana Pliego Zamora, Christopher L. D. McMillan, Benjamin Liang, Nias Y. G. Peng, Julian D. J. Sng, Fatema Tuj Saima, Jenny N. Fung, John D. Lee, Devina Paramitha, Rhys Parry, Michael S. Avumegah, Ariel Isaacs, Martin W. Lo, Zaray Miranda-Chacón, Daniella Bradshaw, Constanza Salinas-Rebolledo, Niwanthi W. Rajapakse, Ernst J. Wolvetang, Trent P. Munro, Alejandro Rojas‐Fernández, Paul R. Young, Katryn J. Stacey, Alexander A. Khromykh, Keith J. Chappell, Daniel Watterson, Trent M. Woodruff

    Izdano 2022
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