Risultati della ricerca - Adam D. Pfefferle

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  1. 1
    Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression

    Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression di Kevin Roarty, Adam D. Pfefferle, Chad J. Creighton, Charles M. Perou, Jeffrey M. Rosen

    Pubblicazione 2017
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  2. 2
    Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential

    Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential di Jelena Knežević, Adam D. Pfefferle, Ivana Petrović, Sandra B. Greene, Charles M. Perou, Jeffrey M. Rosen

    Pubblicazione 2015
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  3. 3
    Oncogenic PI3K Mutations Lead to NF-κB–Dependent Cytokine Expression following Growth Factor Deprivation

    Oncogenic PI3K Mutations Lead to NF-κB–Dependent Cytokine Expression following Growth Factor Deprivation di Jessica E. Hutti, Adam D. Pfefferle, Sean C. Russell, Mayukh Sircar, Charles M. Perou, Albert S. Baldwin

    Pubblicazione 2012
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  4. 4
    Both Noncoding and Protein-Coding RNAs Contribute to Gene Expression Evolution in the Primate Brain

    Both Noncoding and Protein-Coding RNAs Contribute to Gene Expression Evolution in the Primate Brain di Courtney C. Babbitt, Olivier Fédrigo, Adam D. Pfefferle, Alan P. Boyle, Julie E. Horvath, Terrence S. Furey, Gregory A. Wray

    Pubblicazione 2010
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  5. 5
    Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis

    Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis di J. Chuck Harrell, Adam D. Pfefferle, Nicole Zalles, Aleix Prat, Cheng Fan, Andrey Khramtsov, Olufunmilayo I. Olopade, Melissa A. Troester, Andrew C. Dudley, Charles M. Perou

    Pubblicazione 2013
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  6. 6
    Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (<i>NF1</i>) as a Breast Cancer Driver

    Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (<i>NF1</i>) as a Breast Cancer Driver di Marsha D. Wallace, Adam D. Pfefferle, Li Shen, Adrian J. McNairn, Ethan Cerami, Barbara L Fallon, Vera D. Rinaldi, Teresa Southard, Charles M. Perou, John C. Schimenti

    Pubblicazione 2012
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  7. 7
    Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

    Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells di Patrick D. Rädler, Barbara L. Wehde, Aleata A. Triplett, Hridaya Shrestha, Jonathan H. Shepherd, Adam D. Pfefferle, Hallgeir Rui, Robert D. Cardiff, Charles M. Perou, Kay‐Uwe Wagner

    Pubblicazione 2021
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  8. 8
    Mutant <i>PIK3CA</i> accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies

    Mutant <i>PIK3CA</i> accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies di Ariella B. Hanker, Adam D. Pfefferle, Justin M. Balko, María G. Kuba, Christian D. Young, Violeta Sánchez, Cammie R. Sutton, Hailing Cheng, Charles M. Perou, Jean J. Zhao, Rebecca S. Cook, Carlos L. Arteaga

    Pubblicazione 2013
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  9. 9
    Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts

    Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts di Adam D. Pfefferle, Jason I. Herschkowitz, Jerry Usary, J. Chuck Harrell, Benjamin T. Spike, Jessica R. Adams, Maria I. Torres‐Arzayus, Myles Brown, Sean E. Egan, Geoffrey M. Wahl, Jeffrey M. Rosen, Charles M. Perou

    Pubblicazione 2013
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  10. 10
    Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models

    Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models di Patrick J. Roberts, Jerry Usary, David B. Darr, Patrick M. Dillon, Adam D. Pfefferle, Martin C. Whittle, James S. Duncan, Søren M. Johnson, Austin J. Combest, Jian Jin, William C. Zamboni, Gary L. Johnson, Charles M. Perou, Norman E. Sharpless

    Pubblicazione 2012
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  11. 11
    LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

    LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma di Wenjin Liu, Kimberly B. Monahan, Adam D. Pfefferle, Takeshi Shimamura, Jessica A. Sorrentino, Keefe T. Chan, David W. Roadcap, David W. Ollila, Nancy E. Thomas, Diego H. Castrillón, C. Ryan Miller, Charles M. Perou, Kwok‐Kin Wong, James E. Bear, Norman E. Sharpless

    Pubblicazione 2012
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  12. 12
    A randomized phase II/III study of paclitaxel/carboplatin/metformin versus paclitaxel/carboplatin/placebo as initial therapy for measurable stage III or IVA, stage IVB, or recurrent endometrial cancer: An NRG oncology/GOG study

    A randomized phase II/III study of paclitaxel/carboplatin/metformin versus paclitaxel/carboplatin/placebo as initial therapy for measurable stage III or IVA, stage IVB, or recurren... di Victoria Bae‐Jump, Michael W. Sill, Paola A. Gehrig, Jason D. Merker, David L. Corcoran, Adam D. Pfefferle, Michele C. Hayward, Joan L. Walker, Andrea R. Hagemann, Steven Waggoner, Roisin E. O’Cearbhaill, Megan McDonald, Mitchell I. Edelson, Paul DiSilvestro, Amy McNally, Aimee C. Fleury, Ramey D. Littell, Frederick R. Ueland, Heather A. Lankes, Carol Aghajanian

    Pubblicazione 2025
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  13. 13
    c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer

    c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer di Radhika Nair, Daniel Roden, Wee Siang Teo, Andrea McFarland, Simon Junankar, Shengzhi Ye, Akira Nguyen, Jean Yang, Iva Nikolić, Mun N. Hui, Adrienne Morey, Jaynish S. Shah, Adam D. Pfefferle, Jerry Usary, Christina Selinger, Laura A. Baker, Nicola J. Armstrong, Mark J. Cowley, Matthew J. Naylor, Christopher J. Ormandy, Sunil R. Lakhani, Jason I. Herschkowitz, Charles M. Perou, Warren Kaplan, Sandra O’Toole, Alexander Swarbrick

    Pubblicazione 2013
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