Resultats de la cerca - Abigail Altabef

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  1. 1
    CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

    CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer per Edmond Chipumuro, Eugenio Marco, Camilla L. Christensen, Nicholas Kwiatkowski, Tinghu Zhang, Clark M. Hatheway, Brian J. Abraham, Bandana Sharma, Caleb M. Yeung, Abigail Altabef, Antonio R. Pérez‐Atayde, Kwok‐Kin Wong, Guo‐Cheng Yuan, Nathanael S. Gray, Richard A. Young, Rani E. George

    Publicat 2014
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  2. 2
    Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in <i>ALK</i>-Rearranged Non–Small Cell Lung Cancer and Predict Strategies to Overcome Resistance

    Co-Clinical Trials Demonstrate Superiority of Crizotinib to Chemotherapy in <i>ALK</i>-Rearranged Non–Small Cell Lung Cancer and Predict Strategies to Overcome Resistance per Zhao Chen, Esra A. Akbay, Oliver R. Mikse, Tanya Tupper, Katherine A. Cheng, Yuchuan Wang, Xiaohong Tan, Abigail Altabef, Sue-Ann Woo, Liang Chen, Jacob B. Reibel, Pasi A. Jänne, Norman E. Sharpless, Jeffrey A. Engelman, Geoffrey I. Shapiro, Andrew L. Kung, Kwok‐Kin Wong

    Publicat 2013
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  3. 3
    Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

    Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression per Chunxiao Xu, Christine M. Fillmore, Shohei Koyama, Hongbo Wu, Yanqiu Zhao, Chen Zhao, Grit S. Herter-Sprie, Esra A. Akbay, Jeremy H. Tchaicha, Abigail Altabef, Jacob B. Reibel, Zandra E. Walton, Hongbin Ji, Hideo Watanabe, Pasi A. Jänne, Diego H. Castrillón, Anil K. Rustgi, Adam J. Bass, Gordon J. Freeman, Robert F. Padera, Glenn Dranoff, Peter S. Hammerman, Carla F. Kim, Kwok‐Kin Wong

    Publicat 2014
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  4. 4
    Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

    Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR per Qingsong Liu, Chunxiao Xu, Sivapriya Kirubakaran, Xin Zhang, Wooyoung Hur, Yan Liu, Nicholas Kwiatkowski, Jinhua Wang, Kenneth D. Westover, Peng Gao, Dalia Ercan, Mario Niepel, Carson C. Thoreen, Seong A. Kang, Matthew P. Patricelli, Yuchuan Wang, Tanya Tupper, Abigail Altabef, Hidemasa Kawamura, Kathryn D. Held, Danny M. Chou, Stephen J. Elledge, Pasi A. Jänne, Kwok‐Kin Wong, David M. Sabatini, Nathanael S. Gray

    Publicat 2013
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  5. 5
    Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor

    Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor per Camilla L. Christensen, Nicholas Kwiatkowski, Brian J. Abraham, Julián Carretero, Fátima Al‐Shahrour, Tinghu Zhang, Edmond Chipumuro, Grit S. Herter-Sprie, Esra A. Akbay, Abigail Altabef, Jianming Zhang, Takeshi Shimamura, Marzia Capelletti, Jakob B. Reibel, Jillian D. Cavanaugh, Peng Gao, Yan Liu, Signe Regner Michaelsen, Hans Skovgaard Poulsen, Amir Reza Aref, David A. Barbie, James E. Bradner, Rani E. George, Nathanael S. Gray, Richard A. Young, Kwok‐Kin Wong

    Publicat 2014
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  6. 6
    Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

    Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors per Esra A. Akbay, Shohei Koyama, Julián Carretero, Abigail Altabef, Jeremy H. Tchaicha, Camilla L. Christensen, Oliver R. Mikse, Andrew D. Cherniack, Ellen M. Beauchamp, Trevor J. Pugh, Matthew D. Wilkerson, Peter E. Fecci, Mohit Butaney, Jacob B. Reibel, Margaret Soucheray, Travis J. Cohoon, Pasi A. Jänne, Matthew Meyerson, D. Neil Hayes, Geoffrey I. Shapiro, Takeshi Shimamura, Lynette M. Sholl, Scott J. Rodig, Gordon J. Freeman, Peter S. Hammerman, Glenn Dranoff, Kwok‐Kin Wong

    Publicat 2013
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  7. 7
    STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

    STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment per Shohei Koyama, Esra A. Akbay, Yvonne Y. Li, Amir Reza Aref, Ferdinandos Skoulidis, Grit S. Herter-Sprie, Kevin A. Buczkowski, Yan Liu, Mark M. Awad, Warren L. Denning, Lixia Diao, Jing Wang, Edwin R. Parra-Cuentas, Ignacio I. Wistuba, Margaret Soucheray, Tran C. Thai, Hajime Asahina, Shunsuke Kitajima, Abigail Altabef, Jillian D. Cavanaugh, Kevin Rhee, Peng Gao, Haikuo Zhang, Peter E. Fecci, Takeshi Shimamura, Matthew D. Hellmann, John V. Heymach, F. Stephen Hodi, Gordon J. Freeman, David A. Barbie, Glenn Dranoff, Peter S. Hammerman, Kwok‐Kin Wong

    Publicat 2016
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  8. 8
    A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

    A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response per Chen Zhao, Katherine A. Cheng, Zandra E. Walton, Yuchuan Wang, Hiromichi Ebi, Takeshi Shimamura, Yan Liu, Tanya Tupper, Jing Ouyang, Jie Li, Peng Gao, Michele Sue‐Ann Woo, Chunxiao Xu, Masahiko Yanagita, Abigail Altabef, Shumei Wang, Charles Lee, Yuji Nakada, Christopher G. Peña, Yanping Sun, Yoko Franchetti, Catherine Yao, Amy Saur, Michael D. Cameron, Mizuki Nishino, D. Neil Hayes, Matthew D. Wilkerson, Patrick J. Roberts, Carrie B. Lee, Nabeel Bardeesy, Mohit Butaney, Lucian R. Chirieac, Daniel B. Costa, David M. Jackman, Norman E. Sharpless, Diego H. Castrillón, George D. Demetri, Pasi A. Jänne, Pier Paolo Pandolfi, Lewis C. Cantley, Andrew L. Kung, Jeffrey A. Engelman, Kwok‐Kin Wong

    Publicat 2012
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