Sökresultat - Aaron N. Hata

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  1. 1
    Acquired resistance to targeted therapies in NSCLC: Updates and evolving insights

    Acquired resistance to targeted therapies in NSCLC: Updates and evolving insights av Catherine B. Meador, Aaron N. Hata

    Publicerad 2020
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  2. 2
    Emerging Insights into Targeted Therapy-Tolerant Persister Cells in Cancer

    Emerging Insights into Targeted Therapy-Tolerant Persister Cells in Cancer av Heidie Frisco Cabanos, Aaron N. Hata

    Publicerad 2021
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  3. 3
    The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics

    The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics av Aaron N. Hata, Jeffrey A. Engelman, Anthony C. Faber

    Publicerad 2015
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  4. 4
    Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information

    Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information av James Heather, Matthew Spindler, Marta Herrero Alonso, Yifang Shui, David G. Millar, David S. Johnson, Mark Cobbold, Aaron N. Hata

    Publicerad 2022
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  5. 5
    Colon Carcinoma Cell Growth Is Associated with Prostaglandin E2/EP4 Receptor-evoked ERK Activation

    Colon Carcinoma Cell Growth Is Associated with Prostaglandin E2/EP4 Receptor-evoked ERK Activation av Ambra Pozzi, Xuexian Yan, Ines Macias‐Perez, Shouzuo Wei, Aaron N. Hata, Richard Breyer, Jason D. Morrow, Jorge H. Capdevila

    Publicerad 2004
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  6. 6
    Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation

    Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation av Jixiao Niu, Yang Sun, Baoen Chen, Baohui Zheng, Gopala K. Jarugumilli, Sarah R. Walker, Aaron N. Hata, Mari Mino‐Kenudson, David A. Frank, Xu Wu

    Publicerad 2019
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  7. 7
    Patient-Specific Tumor Growth Trajectories Determine Persistent and Resistant Cancer Cell Populations during Treatment with Targeted Therapies

    Patient-Specific Tumor Growth Trajectories Determine Persistent and Resistant Cancer Cell Populations during Treatment with Targeted Therapies av Clemens Grassberger, David M. McClatchy, Changran Geng, Sophia C. Kamran, Florian J. Fintelmann, Yosef E. Maruvka, Zofia Piotrowska, Henning Willers, Lecia V. Sequist, Aaron N. Hata, Harald Paganetti

    Publicerad 2019
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  8. 8
    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells av Sneha Saxena, Christopher S. Nabel, Turner W. Seay, Parasvi S. Patel, Ajinkya S. Kawale, Caroline R. Crosby, Helene Tigro, Eugene Oh, Matthew G. Vander Heiden, Aaron N. Hata, Zucai Suo, Lee Zou

    Publicerad 2024
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  9. 9
    Programmed Cell Death Ligand (PD-L1) Expression in Stage II and III Lung Adenocarcinomas and Nodal Metastases

    Programmed Cell Death Ligand (PD-L1) Expression in Stage II and III Lung Adenocarcinomas and Nodal Metastases av Hironori Uruga, Emine Bozkurtlar, Tiffany G. Huynh, Alona Muzikansky, Yasushi Goto, María Gomez‐Caraballo, Aaron N. Hata, Justin F. Gainor, Eugene J. Mark, Jeffrey A. Engelman, Michael Lanuti, Mari Mino‐Kenudson

    Publicerad 2016
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  10. 10
    Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction

    Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction av Kyle Vaccaro, Juliet Allen, Troy W. Whitfield, Asaf Maoz, Sarah Reeves, José Velarde, Dian Yang, Anna Meglan, Juliano Ribeiro, Jasmine Blandin, Nicole Phan, George W. Bell, Aaron N. Hata, Kipp Weiskopf

    Publicerad 2024
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  11. 11
    Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity

    Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity av Lynnette Marcar, Kankana Bardhan, Liliana Gheorghiu, Patrick Dinkelborg, Heike N. Pfäffle, Qi Liu, Meng Wang, Zofia Piotrowska, Lecia V. Sequist, Kerstin Borgmann, Jeffrey Settleman, Jeffrey A. Engelman, Aaron N. Hata, Henning Willers

    Publicerad 2019
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  12. 12
    Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers

    Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers av Aaron N. Hata, Alan T. Yeo, Anthony C. Faber, Eugene Lifshits, Zhao Chen, Katherine A. Cheng, Zandra E. Walton, Kristopher A. Sarosiek, Anthony Letai, Rebecca S. Heist, Mari Mino‐Kenudson, Kwok‐Kin Wong, Jeffrey A. Engelman

    Publicerad 2014
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  13. 13
    Programmed Cell Death Ligand 1 Expression in Resected Lung Adenocarcinomas: Association with Immune Microenvironment

    Programmed Cell Death Ligand 1 Expression in Resected Lung Adenocarcinomas: Association with Immune Microenvironment av Tiffany G. Huynh, Vicente Morales‐Oyarvide, Meghan Campo, Justin F. Gainor, Emine Bozkurtlar, Hironori Uruga, Ling Zhao, María Gomez‐Caraballo, Aaron N. Hata, Eugene J. Mark, Michael Lanuti, Jeffrey A. Engelman, Mari Mino‐Kenudson

    Publicerad 2016
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  14. 14
    Treatment with Next-Generation ALK Inhibitors Fuels Plasma <i>ALK</i> Mutation Diversity

    Treatment with Next-Generation ALK Inhibitors Fuels Plasma <i>ALK</i> Mutation Diversity av Ibiayi Dagogo‐Jack, Marguerite Rooney, W. Marston Linehan, Rebecca J. Nagy, Beow Y. Yeap, Harper Hubbeling, Emily Chin, Jennifer Ackil, Anna F. Farago, Aaron N. Hata, Jochen K. Lennerz, Justin F. Gainor, Richard B. Lanman, Alice T. Shaw

    Publicerad 2019
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  15. 15
    MUC1-C Is a Common Driver of Acquired Osimertinib Resistance in NSCLC

    MUC1-C Is a Common Driver of Acquired Osimertinib Resistance in NSCLC av Naoki Haratake, Hiroki Ozawa, Yoshihiro Morimoto, Nami Yamashita, Tatsuaki Daimon, Atrayee Bhattacharya, Keyi Wang, Ayako Nakashoji, Hideko Isozaki, Mototsugu Shimokawa, Chie Kikutake, Mikita Suyama, Asato Hashinokuchi, Kazuki Takada, Tomoyoshi Takenaka, Tomoharu Yoshizumi, Tetsuya Mitsudomi, Aaron N. Hata, Donald Küfe

    Publicerad 2023
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  16. 16
    A Phase 2 Study of Capmatinib in Patients With MET-Altered Lung Cancer Previously Treated With a MET Inhibitor

    A Phase 2 Study of Capmatinib in Patients With MET-Altered Lung Cancer Previously Treated With a MET Inhibitor av Ibiayi Dagogo‐Jack, Philicia Moonsamy, Justin F. Gainor, Jochen K. Lennerz, Zofia Piotrowska, W. Marston Linehan, Inga T. Lennes, Lecia V. Sequist, Alice T. Shaw, Kelly Goodwin, Sara E. Stevens, Andrew Do, Subba R. Digumarthy, Kristin S. Price, Alona Muzikansky, Aaron N. Hata, Rebecca S. Heist

    Publicerad 2021
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  17. 17
    TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in <i>BRAF-</i> Mutant Melanoma

    TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in <i>BRAF-</i> Mutant Melanoma av Ryan B. Corcoran, S. Michael Rothenberg, Aaron N. Hata, Anthony C. Faber, Adriano Piris, Rosalynn M. Nazarian, Ronald D. Brown, Jason T. Godfrey, Daniel Winokur, John R. Walsh, Mari Mino‐Kenudson, Shyamala Maheswaran, Jeffrey Settleman, Jennifer A. Wargo, Keith T. Flaherty, Daniel A. Haber, Jeffrey A. Engelman

    Publicerad 2013
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  18. 18
    Targeting TREX1 induces innate immune response in drug-resistant Small Cell Lung Cancer

    Targeting TREX1 induces innate immune response in drug-resistant Small Cell Lung Cancer av Takahiko Murayama, Navin R. Mahadevan, Catherine B. Meador, Elena Ivanova, Yuqiao Pan, Erik H. Knelson, Tetsuo Tani, Jun Nakayama, Xueying Ma, Tran C. Thai, Yin P. Hung, William Kim, Hideo Watanabe, Kathy Q. Cai, Aaron N. Hata, Cloud P. Paweletz, David A. Barbie, Israel Cañadas

    Publicerad 2024
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  19. 19
    Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells

    Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells av Moiez Ali, Min Lu, Hazel X. Ang, Ryan S. Soderquist, Christine E. Eyler, Haley M. Hutchinson, Carolyn Glass, Christopher F. Bassil, Omar Lopez, D. Lucas Kerr, Christina J. Falcon, Helena A. Yu, Aaron N. Hata, Collin M. Blakely, Caroline E. McCoach, Trever G. Bivona, Kris C. Wood

    Publicerad 2022
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  20. 20
    Patterns of Metastatic Spread and Mechanisms of Resistance to Crizotinib in <i>ROS1</i>-Positive Non–Small-Cell Lung Cancer

    Patterns of Metastatic Spread and Mechanisms of Resistance to Crizotinib in <i>ROS1</i>-Positive Non–Small-Cell Lung Cancer av Justin F. Gainor, Diane Tseng, Satoshi Yoda, Ibiayi Dagogo‐Jack, Luc Friboulet, W. Marston Linehan, Harper Hubbeling, Leila Dardaei, Anna F. Farago, Katherine R. Schultz, Lorin A. Ferris, Zofia Piotrowska, James C.H. Hardwick, Donghui Huang, Mari Mino‐Kenudson, A. John Iafrate, Aaron N. Hata, Beow Y. Yeap, Alice T. Shaw

    Publicerad 2017
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