Výsledky vyhledávání

Cordycepin Blocks Lung Injury-Associated Inflammation and Promotes BRCA1-Deficient Breast Cancer Cell Killing by Effectively Inhibiting PARP Autor Hogyoung Kim, Amarjit S. Naura, Youssef Errami, Jihang Ju, A. Hamid Boulares

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Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents Autor Thomas Reiner, Jessica Lacy, Edmund J. Keliher, Katherine S. Yang, Adeeti V. Ullal, Rainer H. Köhler, Claudio Vinegoni, Ralph Weissleder

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ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells Autor Bret R. Adams, Amy J. Hawkins, Lawrence F. Povirk, Kristoffer Valerie

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PARPs and ADP-Ribosylation: 50 Years … and Counting Autor W. Lee Kraus

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Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation Autor Eva Barkauskaite, Gytis Jankevicius, Ivan Ahel

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Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate Autor Aaron J. Gottschalk, Rushi D. Trivedi, Joan Conaway, Ronald Conaway

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The Inhibition and Treatment of Breast Cancer with Poly (ADP-ribose) Polymerase (PARP-1) Inhibitors Autor Joseph Angel De Soto, Xianyan Wang, Yohei Tominaga, Ruihong Wang, Liu Cao, Wenhui Qiao, Cuiling Li, Xiaoling Xu, Amanda P. Skoumbourdis, Sheila A. Prindiville, Craig J. Thomas, Chu‐Xia Deng

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Repair of Topoisomerase I‐Mediated DNA Damage Autor Yves Pommier, Juana Barceló, V. Ashutosh Rao, Olivier Sordet, Andrew G. Jobson, Laurent Thibaut, Ze‐Hong Miao, Jennifer A. Seiler, Hongliang Zhang, Christophe Marchand, Keli Agama, John L. Nitiss, Christophe E. Redon

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Poly(ADP-ribose)-mediated post-translational modification of chromatin-associated human topoisomerase I Autor Usha N. Kasid, Brian Halligan, Leroy F. Liu, Anatoly Dritschilo, Mark E. Smulson

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Angiotensin II-Mediated Endothelial Dysfunction: Role of Poly(ADP-ribose) Polymerase Activation Autor Csaba Szabó, Pál Pacher, Zsuzsanna K. Zsengellér, Anne Vaslin, Katalin Komjáti, Rita Benkő, Min Chen, Jon G. Mabley, Márk Kollai

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Poly(ADP‐ribose) Autor Alexander Bürkle

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Biology of Poly(ADP-Ribose) Polymerases: The Factotums of Cell Maintenance Autor Péter Bai

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PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function Autor Mohamed A. Ghonim, Kusma Pyakurel, Salomè V. Ibba, Amir A. Al-Khami, Jeffrey Wang, Paulo C. Rodrı́guez, Hamada F. Rady, Ali H. El‐Bahrawy, Matthew R. Lammi, Moselhy S. Mansy, Kamel Al-Ghareeb, Alistair J. Ramsay, Augusto C. Ochoa, Amarjit S. Naura, A. Hamid Boulares

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Hypoglycemic Neuronal Death and Cognitive Impairment Are Prevented by Poly(ADP-Ribose) Polymerase Inhibitors Administered after Hypoglycemia Autor Sang Won Suh, Koji Aoyama, Yongmei Chen, Philippe Garnier, Yasuhiko Matsumori, Elizabeth T. Gum, Jialing Liu, Raymond A. Swanson

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Depletion of poly(ADP-ribose) polymerase by antisense RNA expression results in a delay in DNA strand break rejoining. Autor Rui Ding, Yves Pommier, V Kang, Mark E. Smulson

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8‐Oxo‐7,8‐dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients Autor Tomasz Dziaman, Zbigniew Banaszkiewicz, Krzysztof Roszkowski, Daniel Gackowski, Ewa Wiśniewska, Rafał Różalski, Marek Foksiński, Agnieszka Siomek, Elżbieta Speina, Alicja Winczura, Andrzej Marszałek, Barbara Tudek, Ryszard Oliński

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Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: <i>PALB2</i> mutation predicts exceptional <i>in vivo</i> response to BMN 673 Autor Malcolm A. Smith, Oliver Hampton, C. Patrick Reynolds, Min H. Kang, John M. Maris, Richard Görlick, E. Anders Kolb, Richard B. Lock, Hernán Carol, Stephen T. Keir, Jianrong Wu, Raushan T. Kurmasheva, David A. Wheeler, Peter J. Houghton

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E2 of Hepatitis C Virus Inhibits Apoptosis Autor Song Hee Lee, Yoon Ki Kim, Chon Saeng Kim, Su Kyoung Seol, Joonhyun Kim, Sungchan Cho, Young-Lan Song, Ralf Bartenschlager, Sung Key Jang

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Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube canc... Autor Ruud van der Noll, Serena Marchetti, Neeltje Steeghs, Jos H. Beijnen, Marja Mergui‐Roelvink, Emmy Harms, Harriet Rehorst, Gabe S. Sonke, Jan H.M. Schellens

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Mechanism of the inhibition of Ca2+, Mg2+-dependent endonuclease of bull seminal plasma induced by ADP-ribosylation. Autor Yoshito Tanaka, K. Yoshihara, Asako Itaya, T. Kamiya, S. S. Koide

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