Risultati della ricerca

Schwannomas and Their Pathogenesis di David A. Hilton, C. Oliver Hanemann

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Hyperactive Transforming Growth Factor-β1 Signaling Potentiates Skeletal Defects in a Neurofibromatosis Type 1 Mouse Model di Steven D. Rhodes, Xiaohua Wu, Yongzheng He, Shi Chen, Hao Yang, Karl Staser, Jiapeng Wang, Ping Zhang, Chang Jiang, Hiroki Yokota, Ruizhi Dong, Xianghong Peng, Xianlin Yang, Sreemala Murthy, Mohamad Azhar, Khalid S. Mohammad, Mingjiang Xu, Theresa A. Guise, Feng‐Chun Yang

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Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determini... di John F. Eccleston, Keith J. M. Moore, Leslie K. Morgan, Richard Skinner, Peter N. Lowe

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Characterization of full-length neurofibromin: tubulin inhibits Ras GAP activity. di Gideon Bollag, Frank McCormick, R Clark

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Identification of a human rasGAP-related protein containing calmodulin-binding motifs. di Lawrence Weissbach, Jeffrey Settleman, Matthew F. Kalady, Allard J. Snijders, Anita E. Murthy, Yirui Yan, André Bernards

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The Neurofibromatosis 1 Gene Product Neurofibromin Regulates Pituitary Adenylate Cyclase-Activating Polypeptide-Mediated Signaling in Astrocytes di Biplab Dasgupta, Laura L. Dugan, David H. Gutmann

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Hepatic neurofibromatosis, malignant schwannoma, and angiosarcoma in von Recklinghausen's disease di Seth Lederman, Éric Martin, Karen T. Laffey, Jay H. Lefkowitch

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Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons di Michael L. Nordlund, Xiaosong Gu, MT Shipley, Nancy Ratner

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Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function. di M R Johnson, Jeffrey E. DeClue, Sylvia Felzmann, William C. Vass, Guangwen Xu, R. White, Douglas R. Lowy

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Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation di Gerald J. Sun, Yi Zhou, Shiori Ito, Michael A. Bonaguidi, Genevieve Stein-O’Brien, Nicholas K. Kawasaki, Nikhil Modak, Yuan Zhu, Guo‐li Ming, Hongjun Song

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A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions. di Midori Maekawa, Shuhui Li, Akihiro Iwamatsu, Takashi Morishita, Kyoko Yokota, Y. Imai, Shinichi Kohsaka, Shun Nakamura, Satoshi Hattori

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Reduced microglial <scp>CX3CR1</scp> expression delays neurofibromatosis‐1 glioma formation di Winnie W. Pong, Samantha B. Higer, Scott M. Gianino, Ryan J. Emnett, David H. Gutmann

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Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways di Yi‐Hsien Chen, Scott M. Gianino, David H. Gutmann

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A Conserved Alternative Splice in the von Recklinghausen Neurofibromatosis (<i>NF1</i>) Gene Produces Two Neurofibromin Isoforms, Both of Which Have GTPase-Activating Protein Activ... di Lone B. Andersen, Roymarie Ballester, Douglas A. Marchuk, Eric C. Chang, David H. Gutmann, Ann M. Saulino, Jacques Camonis, Michael Wigler, Francis S. Collins

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ralGDS family members interact with the effector loop of ras p21. di Akira Kikuchi, Susan D. Demo, Z H Ye, Y W Chen, L T Williams

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Homozygous Inactivation of the<i>NF1</i>Gene in Bone Marrow Cells from Children with Neurofibromatosis Type 1 and Malignant Myeloid Disorders di Lucy Side, Brigit R. Taylor, Matthew C. Cayouette, Edward Conner, Patricia Thompson, Michael C. Luce, Kevin Shannon

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NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development di Efrain Sanchez‐Ortiz, Woosung Cho, Inga Nazarenko, Wei Mo, Jian Chen, Luis F. Parada

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MicroRNA‐10b regulates tumorigenesis in neurofibromatosis type 1 di Guolin Chai, Ning Liu, Junrong Ma, Hua Li, Janet L. Oblinger, Agasanur K. Prahalad, Meng Gong, Long‐Sheng Chang, Margaret R. Wallace, David Muir, Abhijit Guha, Roger Phipps, Janet M. Hock, Xijie Yu

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins di Roymarie Ballester, Douglas A. Marchuk, Mark S. Boguski, Ann Saulino, Roxanne Letcher, Michael Wigler, Francis S. Collins

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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors di Walter J. Jessen, Shyra J. Miller, Edwin Jousma, Jianqiang Wu, Tilat A. Rizvi, Meghan E. Brundage, David Eaves, Brigitte C. Widemann, Mi‐Ok Kim, Eva Dombi, Jessica Sabo, Atira Hardiman Dudley, Michiko Niwa‐Kawakita, Grier P. Page, Marco Giovannini, Bruce J. Aronow, Timothy P. Cripe, Nancy Ratner

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