Suchergebnisse

Schwannomas and Their Pathogenesis von David A. Hilton, C. Oliver Hanemann

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Hyperactive Transforming Growth Factor-β1 Signaling Potentiates Skeletal Defects in a Neurofibromatosis Type 1 Mouse Model von Steven D. Rhodes, Xiaohua Wu, Yongzheng He, Shi Chen, Hao Yang, Karl Staser, Jiapeng Wang, Ping Zhang, Chang Jiang, Hiroki Yokota, Ruizhi Dong, Xianghong Peng, Xianlin Yang, Sreemala Murthy, Mohamad Azhar, Khalid S. Mohammad, Mingjiang Xu, Theresa A. Guise, Feng‐Chun Yang

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Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determini... von John F. Eccleston, Keith J. M. Moore, Leslie K. Morgan, Richard Skinner, Peter N. Lowe

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Characterization of full-length neurofibromin: tubulin inhibits Ras GAP activity. von Gideon Bollag, Frank McCormick, R Clark

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Identification of a human rasGAP-related protein containing calmodulin-binding motifs. von Lawrence Weissbach, Jeffrey Settleman, Matthew F. Kalady, Allard J. Snijders, Anita E. Murthy, Yirui Yan, André Bernards

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The Neurofibromatosis 1 Gene Product Neurofibromin Regulates Pituitary Adenylate Cyclase-Activating Polypeptide-Mediated Signaling in Astrocytes von Biplab Dasgupta, Laura L. Dugan, David H. Gutmann

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Hepatic neurofibromatosis, malignant schwannoma, and angiosarcoma in von Recklinghausen's disease von Seth Lederman, Éric Martin, Karen T. Laffey, Jay H. Lefkowitch

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Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons von Michael L. Nordlund, Xiaosong Gu, MT Shipley, Nancy Ratner

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Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function. von M R Johnson, Jeffrey E. DeClue, Sylvia Felzmann, William C. Vass, Guangwen Xu, R. White, Douglas R. Lowy

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Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation von Gerald J. Sun, Yi Zhou, Shiori Ito, Michael A. Bonaguidi, Genevieve Stein-O’Brien, Nicholas K. Kawasaki, Nikhil Modak, Yuan Zhu, Guo‐li Ming, Hongjun Song

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A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions. von Midori Maekawa, Shuhui Li, Akihiro Iwamatsu, Takashi Morishita, Kyoko Yokota, Y. Imai, Shinichi Kohsaka, Shun Nakamura, Satoshi Hattori

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Reduced microglial <scp>CX3CR1</scp> expression delays neurofibromatosis‐1 glioma formation von Winnie W. Pong, Samantha B. Higer, Scott M. Gianino, Ryan J. Emnett, David H. Gutmann

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Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways von Yi‐Hsien Chen, Scott M. Gianino, David H. Gutmann

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A Conserved Alternative Splice in the von Recklinghausen Neurofibromatosis (<i>NF1</i>) Gene Produces Two Neurofibromin Isoforms, Both of Which Have GTPase-Activating Protein Activ... von Lone B. Andersen, Roymarie Ballester, Douglas A. Marchuk, Eric C. Chang, David H. Gutmann, Ann M. Saulino, Jacques Camonis, Michael Wigler, Francis S. Collins

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ralGDS family members interact with the effector loop of ras p21. von Akira Kikuchi, Susan D. Demo, Z H Ye, Y W Chen, L T Williams

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Homozygous Inactivation of the<i>NF1</i>Gene in Bone Marrow Cells from Children with Neurofibromatosis Type 1 and Malignant Myeloid Disorders von Lucy Side, Brigit R. Taylor, Matthew C. Cayouette, Edward Conner, Patricia Thompson, Michael C. Luce, Kevin Shannon

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NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development von Efrain Sanchez‐Ortiz, Woosung Cho, Inga Nazarenko, Wei Mo, Jian Chen, Luis F. Parada

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MicroRNA‐10b regulates tumorigenesis in neurofibromatosis type 1 von Guolin Chai, Ning Liu, Junrong Ma, Hua Li, Janet L. Oblinger, Agasanur K. Prahalad, Meng Gong, Long‐Sheng Chang, Margaret R. Wallace, David Muir, Abhijit Guha, Roger Phipps, Janet M. Hock, Xijie Yu

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins von Roymarie Ballester, Douglas A. Marchuk, Mark S. Boguski, Ann Saulino, Roxanne Letcher, Michael Wigler, Francis S. Collins

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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors von Walter J. Jessen, Shyra J. Miller, Edwin Jousma, Jianqiang Wu, Tilat A. Rizvi, Meghan E. Brundage, David Eaves, Brigitte C. Widemann, Mi‐Ok Kim, Eva Dombi, Jessica Sabo, Atira Hardiman Dudley, Michiko Niwa‐Kawakita, Grier P. Page, Marco Giovannini, Bruce J. Aronow, Timothy P. Cripe, Nancy Ratner

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