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  1. 1
    Diagnostic Testing for IDH1 and IDH2 Variants in Acute Myeloid Leukemia

    Diagnostic Testing for IDH1 and IDH2 Variants in Acute Myeloid Leukemia Autor Keyur P. Patel, Bedia A. Barkoh, Chen Zhao, Deqin Ma, Neelima Reddy, L. Jeffrey Medeiros, Rajyalakshmi Luthra

    Vydáno 2011
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  2. 2
    ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia

    ASXL1 mutation is associated with poor prognosis and acute transformation in chronic myelomonocytic leukaemia Autor Véronique Gelsi‐Boyer, Virginie Trouplin, Julien Roquain, José Adélaı̈de, Nadine Carbuccia, Benjamin Esterni, Pascal Finetti, Anne Murati, Christine Arnoulet, Hacène Zerazhi, Hacène Fezoui, Z Tadrist, Meyer Nezri, Max Chaffanet, Julien Mozziconacci, Norbert Vey, Daniel Birnbaum

    Vydáno 2010
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  3. 3
    Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53‐mediated cellular senescence

    Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53‐mediated cellular senescence Autor John C.T. Wong, Mohammad R. Hasan, Mahbuba Rahman, Angel C.Y. Yu, Simon K. Chan, David F. Schaeffer, Hagen F. Kennecke, Howard J. Lim, David Owen, Isabella T. Tai

    Vydáno 2013
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  4. 4
    Prognostic significance of alterations in IDH enzyme isoforms in patients with AML treated with high‐dose cytarabine and idarubicin

    Prognostic significance of alterations in IDH enzyme isoforms in patients with AML treated with high‐dose cytarabine and idarubicin Autor Farhad Ravandi, Keyur P. Patel, Rajyalakshmi Luthra, Stefan Faderl, Marina Konopleva, Tapan M. Kadia, Mark Brandt, Sherry Pierce, Steven M. Kornblau, Michael Andreeff, Xuemei Wang, Guillermo Garcia‐Manero, Jorge E. Cortés, Hagop M. Kantarjian

    Vydáno 2011
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  5. 5
    Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination

    Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination Autor Helena Johansson, Stina Simonsson

    Vydáno 2010
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  6. 6
    Subclones with the t(9;22)/<i>BCR‐ABL1</i> rearrangement occur in AML and seem to cooperate with distinct genetic alterations

    Subclones with the t(9;22)/<i>BCR‐ABL1</i> rearrangement occur in AML and seem to cooperate with distinct genetic alterations Autor Ulrike Bacher, Torsten Haferlach, Tamara Alpermann, Melanie Zenger, Andreas Hochhaus, Dietrich W. Beelen, M. Uppenkamp, Mathias Rummel, Wolfgang Kern, Susanne Schnittger, Claudia Haferlach

    Vydáno 2011
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  7. 7
    Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties

    Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties Autor Mattia Poletto, Matilde Clarissa Malfatti, Dorjbal Dorjsuren, Pasqualina Liana Scognamiglio, Daniela Marasco, Carlo Vascotto, Ajit Jadhav, David J. Maloney, David M. Wilson, Anton Simeonov, Gianluca Tell

    Vydáno 2015
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  8. 8
    Characteristics, clinical outcome, and prognostic significance of <scp>IDH</scp> mutations in <scp>AML</scp>

    Characteristics, clinical outcome, and prognostic significance of <scp>IDH</scp> mutations in <scp>AML</scp> Autor Courtney D. DiNardo, Farhad Ravandi, Sam Agresta, Marina Konopleva, Koichi Takahashi, Tapan M. Kadia, Mark J. Routbort, Keyur P. Patel, Mark Brandt, Sherry Pierce, Guillermo Garcia‐Manero, Jorge E. Cortés, Hagop M. Kantarjian

    Vydáno 2015
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  9. 9
    DNMT3A R882 Mutation with FLT3-ITD Positivity Is an Extremely Poor Prognostic Factor in Patients with Normal-Karyotype Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation

    DNMT3A R882 Mutation with FLT3-ITD Positivity Is an Extremely Poor Prognostic Factor in Patients with Normal-Karyotype Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Tr... Autor Jae‐Sook Ahn, Hyeoung‐Joon Kim, Yeo‐Kyeoung Kim, Seun-Shin Lee, Sung‐Hoon Jung, Deok‐Hwan Yang, Je‐Jung Lee, Nan Young Kim, Seung Hyun Choi, Chul Won Jung, Jun‐Ho Jang, Hee‐Je Kim, Joon Ho Moon, Sang Kyun Sohn, Jong-Ho Won, Sung‐Hyun Kim, Dennis Dong Hwan Kim

    Vydáno 2015
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  10. 10
    Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the ALFA-0701 trial

    Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: Results of the... Autor Aline Renneville, Raouf Ben Abdelali, Sylvie Chevret, Olivier Nibourel, Meyling Cheok, Cécile Pautas, Rémy Dulery, Thomas Boyer, Jean‐Michel Cayuela, Sandrine Hayette, Emmanuel Raffoux, H. Farhat, Nicolas Boissel, Christine Terré, Hervé Dombret, Sylvie Castaigné, Claude Preudhomme

    Vydáno 2014
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  11. 11
    A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies<i>FLT3</i>-Mutated Clones in Acute Myeloid Leukemia

    A Leukemia-Associated CD34/CD123/CD25/CD99+ Immunophenotype Identifies<i>FLT3</i>-Mutated Clones in Acute Myeloid Leukemia Autor Daniela F. Angelini, Tiziana Ottone, Gisella Guerrera, Serena Lavorgna, Michela Cittadini, Francesco Buccisano, Marco De Bardi, Francesca Gargano, Luca Maurillo, Mariadomenica Divona, Nélida I. Noguera, Maria Irno Consalvo, Giovanna Borsellino, Giorgio Bernardi, Sergio Amadori, Adriano Venditti, Luca Battistini, Francesco Lo‐Coco

    Vydáno 2015
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  12. 12
    NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells

    NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells Autor Yi Zhu, Minmin Shi, Hao Chen, Jiangning Gu, Jiaqiang Zhang, Baiyong Shen, Xiaxing Deng, Junjie Xie, Xi Zhan, Chenghong Peng

    Vydáno 2015
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  13. 13
    Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome

    Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a fa... Autor Bas J. Wouters, Bob Löwenberg, Claudia Erpelinck-Verschueren, Wim L.J. van Putten, Peter J.M. Valk, Ruud Delwel

    Vydáno 2009
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  14. 14
    Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)

    Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML) Autor Christian Thiede, Sina Koch, Eva Creutzig, Christine Steudel, Thomas Illmer, Markus Schaich, Gerhard Ehninger

    Vydáno 2006
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  15. 15
    The Structure and Functions of NPM1/Nucleophsmin/B23, a Multifunctional Nucleolar Acidic Protein

    The Structure and Functions of NPM1/Nucleophsmin/B23, a Multifunctional Nucleolar Acidic Protein Autor Mitsuru Okuwaki

    Vydáno 2007
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  16. 16
    Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center

    Resistance prediction in AML: analysis of 4601 patients from MRC/NCRI, HOVON/SAKK, SWOG and MD Anderson Cancer Center Autor Roland B. Walter, Megan Othus, Alan K. Burnett, Bob Löwenberg, H. Kantarjian, Gert J. Ossenkoppele, Robert K. Hills, Farhad Ravandi, Thomas Pabst, Anna Evans, Sherry R. Pierce, Marie‐Christiane Vekemans, Frederick R. Appelbaum, Elihu H. Estey

    Vydáno 2014
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  17. 17
    Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases

    Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases Autor Chi Young Ok, Keyur P. Patel, Guillermo Garcia‐Manero, Mark J. Routbort, Bin Fu, Guilin Tang, Maitrayee Goswami, Rajesh R. Singh, Rashmi Kanagal‐Shamanna, Sherry Pierce, Ken H. Young, Hagop M. Kantarjian, L. Jeffrey Medeiros, Rajyalakshmi Luthra, Sa A. Wang

    Vydáno 2014
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  18. 18
    Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia

    Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia Autor Carlos Santamaría, Carmen Chillón, Ramón García‐Sánz, Cristina Pérez, Marı́a Dolores Caballero, Fernando Ramos, Alfonso García de Coca, José María Alonso, Pilar Giraldo, Teresa Bernal, José Antonio Queizán, N. Rodríguez, Pascual Fernández, Abelardo Bárez, María Jesús Peñarrubia, Ana Balanzategui, María‐Belén Vidriales, María Eugenia Sarasquete, Miguel Alcoceba, Joaquı́n Dı́az-Mediavilla, Jesús F. San Miguel, Marcos González

    Vydáno 2009
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  19. 19
    Importância da detecção das mutações no gene FLT3 e no gene NPM1 na leucemia mieloide aguda - Classificação da Organização Mundial de Saúde 2008

    Importância da detecção das mutações no gene FLT3 e no gene NPM1 na leucemia mieloide aguda - Classificação da Organização Mundial de Saúde 2008 Autor Júlio Licinio, Maria Cláudia Santos‐Silva

    Vydáno 2010
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  20. 20
    Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations

    Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations Autor Wen‐Chien Chou, Huai‐Hsuan Huang, Hsin‐An Hou, Chien‐Yuan Chen, Jih‐Luh Tang, Ming Yao, Woei Tsay, Bor‐Sheng Ko, Shang‐Ju Wu, Shang‐Yi Huang, Szu-Chun Hsu, Yao‐Chang Chen, Yen-Ning Huang, Yi-Chang Chang, Fen‐Yu Lee, Min-Chih Liu, Chia‐Wen Liu, Mei‐Hsuan Tseng, Chi‐Fei Huang, Hwei‐Fang Tien

    Vydáno 2010
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