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  1. 1
    Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer

    Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer mā Adam R. Blanden, Xin Yu, Stewart N. Loh, Arnold J. Levine, Darren R. Carpizo

    I whakaputaina 2015
    Whiwhi kuputuhi katoa
    Revisão
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  2. 2
    Structure of <scp>C</scp>lass <scp>B GPCRs</scp>: new horizons for drug discovery

    Structure of <scp>C</scp>lass <scp>B GPCRs</scp>: new horizons for drug discovery mā Andrea Bortolato, A.S. Dore, Kaspar Hollenstein, Benjamin G. Tehan, Jonathan S. Mason, Fiona H. Marshall

    I whakaputaina 2014
    Whiwhi kuputuhi katoa
    Revisão
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  3. 3
    Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: <scp>IUPHAR R</scp>eview 12

    Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: <scp>IUPHAR R</scp>eview 12 mā Janet J. Maguire, Anthony P. Davenport

    I whakaputaina 2014
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Revisão
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  4. 4
    A Research Agenda for Malaria Eradication: Basic Science and Enabling Technologies

    A Research Agenda for Malaria Eradication: Basic Science and Enabling Technologies

    I whakaputaina 2011
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Revisão
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  5. 5
    Unfolded protein response to autophagy as a promising druggable target for anticancer therapy

    Unfolded protein response to autophagy as a promising druggable target for anticancer therapy mā Dong Hoon Suh, Mi‐Kyung Kim, Hee Seung Kim, Hyun Hoon Chung, Yong Sang Song

    I whakaputaina 2012
    Whiwhi kuputuhi katoa
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  6. 6
    The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro

    The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro mā Olga Piskareva, Harry Harvey, John Nolan, Ross Conlon, Leah Alcock, Patrick G. Buckley, Paul Dowling, Michael Henry, Finbarr O’Sullivan, Isabella Bray, Raymond L. Stallings

    I whakaputaina 2015
    Whiwhi kuputuhi katoa
    Artigo
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  7. 7
    An integrated structural proteomics approach along the druggable genome of Corynebacterium pseudotuberculosis species for putative druggable targets

    An integrated structural proteomics approach along the druggable genome of Corynebacterium pseudotuberculosis species for putative druggable targets mā Leandro G. Radusky, Syed Shah Hassan, Esteban Lanzarotti, Sandeep Tiwari, Syed Babar Jamal, Javed Ali, Amjad Ali, Rafaela Salgado Ferreira, Debmalya Barh, Artur Silva, Adrián G. Turjanski, Vasco Azevedo

    I whakaputaina 2015
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  8. 8
    Molecular targeted therapy in the treatment of advanced stage non-small cell lung cancer (NSCLC)

    Molecular targeted therapy in the treatment of advanced stage non-small cell lung cancer (NSCLC) mā Nesaretnam Barr Kumarakulasinghe, Nico van Zanwijk, Ross A. Soo

    I whakaputaina 2015
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Revisão
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  9. 9
    A microRNA code for prostate cancer metastasis

    A microRNA code for prostate cancer metastasis mā Désirée Bonci, Valeria Coppola, Michele Patrizii, Antonio Addario, Alessio Cannistraci, Federica Francescangeli, Raffaella Pecci, Giovanni Muto, Devis Collura, R. Bedini, Ann Zeuner, M Valtieri, Steno Sentinelli, Maria Serena Benassi, Michele Gallucci, Paolo Carlini, Stefano Piccolo, Ruggero De Maria

    I whakaputaina 2015
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  10. 10
    Mapping the Druggable Allosteric Space of G‐Protein Coupled Receptors: a Fragment‐Based Molecular Dynamics Approach

    Mapping the Druggable Allosteric Space of G‐Protein Coupled Receptors: a Fragment‐Based Molecular Dynamics Approach mā Anthony Ivetac, J. Andrew McCammon

    I whakaputaina 2010
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  11. 11
    A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets

    A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets mā Joost C.M. Uitdehaag, Folkert Verkaar, Husam Alwan, Jos de Man, Rogier C. Buijsman, Guido J.R. Zaman

    I whakaputaina 2012
    Whiwhi kuputuhi katoa
    Revisão
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  12. 12
    Machine learning models identify molecules active against the Ebola virus in vitro

    Machine learning models identify molecules active against the Ebola virus in vitro mā Sean Ekins, Joel S. Freundlich, Alex M. Clark, Manu Anantpadma, Robert A. Davey, Peter B. Madrid

    I whakaputaina 2017
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Pré-impressão
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  13. 13
    A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

    A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells mā Micah J. Niphakis, Kenneth M. Lum, Armand B. Cognetta, Bruno E. Correia, Taka-Aki Ichu, José Olucha, Steven J Brown, Soumajit Kundu, Fabiana Piscitelli, Hugh Rosen, Benjamin F. Cravatt

    I whakaputaina 2015
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  14. 14
    Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1

    Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1 mā Mattia Mori, Lesia Kovalenko, Sébastien Lyonnais, Danny Antaki, Bruce E. Torbett, Maurizio Botta, Gilles Mirambeau, Yves Mély

    I whakaputaina 2015
    Whiwhi kuputuhi katoa
    Revisão
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  15. 15
    Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily

    Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily mā Bryan L. Roth, Wesley K. Kroeze

    I whakaputaina 2015
    Whiwhi kuputuhi katoa
    Revisão
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  16. 16
    Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

    Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity mā Bret D. Wallace, Adam Roberts, Rebecca M. Pollet, James D. Ingle, Kristen A. Biernat, Samuel J. Pellock, Madhu Kumar Venkatesh, Leah Guthrie, Sara O’Neal, Sara J. Robinson, Makani Dollinger, Esteban G. Figueroa, Sarah R. McShane, Rachel D. Cohen, Jian Jin, Stephen V. Frye, William C. Zamboni, Charles Pepe‐Ranney, Sridhar Mani, Libusha Kelly, Matthew R. Redinbo

    I whakaputaina 2015
    Whiwhi kuputuhi katoa
    Artigo
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  17. 17
    SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets

    SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets mā Jing Guo, Hui Liu, Jie Zheng

    I whakaputaina 2015
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  18. 18
    DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

    DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts mā David Roulois, Helen Loo Yau, Rajat Singhania, Yadong Wang, Arnavaz Danesh, Shu Yi Shen, Han Han, Gangning Liang, Peter A. Jones, Trevor J. Pugh, Catherine O’Brien, Daniel D. De Carvalho

    I whakaputaina 2015
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  19. 19
    Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy

    Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted t... mā Elisa Donnard, Paula Fontes Asprino, Bruna Corrêa, Fabiana Bettoni, Fernanda Christtanini Koyama, Fábio C. P. Navarro, Rodrigo Oliva Perez, John M. Mariadason, Oliver M. Sieber, Robert L. Strausberg, Andrew J.G. Simpson, Denis L. Jardim, Luiz F. L. Reis, Raphael B. Parmigiani, Pedro A. F. Galante, Anamaria A. Camargo

    I whakaputaina 2014
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  20. 20
    Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors.

    Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors. mā Giulia Taraboletti, Marco Rusnati, Laura Ragona, Giorgio Colombo

    I whakaputaina 2010
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Revisão
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