檢索結果

Current and novel therapeutic molecules and targets in Alzheimer's disease 由 Ashwini Kumar, Chaluveelaveedu Murleedharan Nisha, Chitrangda Silakari, Isha Sharma, Kanukanti Anusha, Nityasha Gupta, Prateek Nair, Timir Tripathi, Awanish Kumar

獲取全文

Oxidative Stress in Neurodegenerative Diseases 由 Ewa Niedzielska, Irena Smaga, Maciej Gawlik, Andrzej Moniczewski, Piotr Stankowicz, Joanna Pera, Małgorzata Filip

獲取全文 獲取全文

Can functional magnetic resonance imaging improve success rates in central nervous system drug discovery? 由 David Borsook, Richard Hargreaves, Lino Becerra

獲取全文

New paradigms in GPCR drug discovery 由 Kenneth A. Jacobson

獲取全文

Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling 由 Åsmund Flobak, Anaı̈s Baudot, Élisabeth Rémy, Liv Thommesen, Denis Thieffry, Martin Kuiper, Astrid Lægreid

獲取全文 獲取全文

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics 由 John L. Wallace, Rory W. Blackler, Melissa V. Chan, Gabriela Silva, Wagdi Elsheikh, Kyle L. Flannigan, Iulia Gamaniek, Anna Mańko, Lu Wang, Jean‐Paul Motta, André G. Buret

獲取全文

A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity 由 Nico Scheer, Ian D. Wilson

獲取全文

Challenges and opportunities for non-antibody scaffold drugs 由 Rodrigo Vazquez-Lombardi, Tri Giang Phan, Carsten Zimmermann, David C. Lowe, Lutz Jermutus, Daniel Christ

獲取全文

Physiologically Based Pharmacokinetics Is Impacting Drug Development and Regulatory Decision Making 由 Malcolm Rowland, LJ Lesko, Amin Rostami‐Hodjegan

獲取全文 獲取全文

The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link 由 Laura W. Bowers, Emily L. Rossi, Ciara H. Oâ€TMFlanagan, Linda A. deGraffenried, Stephen D. Hursting

獲取全文 獲取全文

Identification of new epilepsy treatments: Issues in preclinical methodology 由 Aristea S. Galanopoulou, Paul S. Buckmaster, Kevin J. Staley, Solomon L. Moshé, Emilio Perucca, Jerome Engel, Wolfgang Löscher, Jeffrey L. Noebels, Asla Pitkänen, James P. Stables, H. Steve White, Terence J. O’Brien, Michele Simonato

獲取全文

NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress 由 Becky A. Diebold, Susan M. Smith, Li Yang, J. David Lambeth

獲取全文

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential—towards a consensus 由 Geoffrey T. Tucker, J. Brian Houston, Shiew‐Mei Huang

獲取全文

Bacterial proteins and peptides in cancer therapy 由 Ananda M. Chakrabarty, Nuno Bernardes, Arsénio M. Fialho

獲取全文 獲取全文

Interleukins in glioblastoma pathophysiology: implications for therapy 由 YT Yeung, KL McDonald, Thomas Grewal, Lenka Munoz

獲取全文

Mechanisms and modulation of resistance to chemotherapy in ovarian cancer 由 Raymond P. Perez, Thomas C. Hamilton, Robert F. Ozols, Robert C. Young

獲取全文 獲取全文

Monoamine oxidase: radiotracer chemistry and human studies 由 Joanna S. Fowler, Jean Logan, Elena Shumay, Nelly Alia‐Klein, Gene‐Jack Wang, Nora D. Volkow

獲取全文

Therapeutic Antibodies: Current State and Future Trends – Is a Paradigm Change Coming Soon? 由 Dimiter S. Dimitrov, James D. Marks

獲取全文

Recent Trends in Therapeutic Approaches for Diabetes Management: A Comprehensive Update 由 Pragya Tiwari

獲取全文 獲取全文

Early Implementation of QbD in Biopharmaceutical Development: A Practical Example 由 Jesús Zurdo, Andreas Arnell, Olga Obrezanova, Noel Smith, Ramón Gómez de la Cuesta, Thomas R. A. Gallagher, Rebecca Michael, Yvette Stallwood, Caroline Ekblad, Lars Abrahmsén, Ingmarie Höidén‐Guthenberg

獲取全文 獲取全文