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  1. 1
    Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells

    Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells di Daochuan Li, Bryan Mackowiak, Timothy G. Brayman, Michael D. Mitchell, Lei Zhang, Shiew‐Mei Huang, Hongbing Wang

    Pubblicazione 2015
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  2. 2
    Estrogen Receptor α Mediates 17α-Ethynylestradiol Causing Hepatotoxicity

    Estrogen Receptor α Mediates 17α-Ethynylestradiol Causing Hepatotoxicity di Yukio Yamamoto, Rick Moore, Holly A. Hess, Grace L. Guo, Frank J. Gonzalez, Kenneth S. Korach, Robert R. Maronpot, Masahiko Negishi

    Pubblicazione 2006
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  3. 3
    Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes

    Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes di Alice Rulcová, Ilona Prokopová, Lucie Krausová, Michal Bitman, Radim Vrzal, Zdeněk Dvořák, J Blahoš, Petr Pávek

    Pubblicazione 2010
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  4. 4
    Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors

    Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors di Marina Grimaldi, Abdelhay Boulahtouf, V. Delfosse, Erwan Thouënnon, William Bourguet, Patrick Balaguer

    Pubblicazione 2015
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  5. 5
    Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor

    Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor di Eugenia Hoffart, Luam Ghebreghiorghis, AK Nüssler, WE Thasler, Thomas S. Weiß, Matthias Schwab, Oliver Burk

    Pubblicazione 2011
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  6. 6
    Caffeine increases Nr1i3 expression and potentiates the effects of its ligand, TCPOBOP, in mice liver

    Caffeine increases Nr1i3 expression and potentiates the effects of its ligand, TCPOBOP, in mice liver di Heidge Fukumasu, Arina Lázaro Rochetti, Andréia Oliveira Latorre, Pedro Ratto Lisboa Pires, Tereza Cristina Silva, M.L. Dagli

    Pubblicazione 2015
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  7. 7
    Dual effect of dexamethasone on <i>CYP3A4</i> gene expression in human hepatocytes

    Dual effect of dexamethasone on <i>CYP3A4</i> gene expression in human hepatocytes di Jean‐Marc Pascussi, Lionel Drocourt, Sabine Gerbal‐Chaloin, Jean‐Michel Fabre, Patrick Maurel, Marie‐José Vilarem

    Pubblicazione 2001
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  8. 8
    Hepatoprotective role of PXR activation and MRP3 in cholic acid‐induced cholestasis

    Hepatoprotective role of PXR activation and MRP3 in cholic acid‐induced cholestasis di Shirley Teng, Micheline Piquette‐Miller

    Pubblicazione 2007
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  9. 9
    The Nuclear Pregnane X Receptor Regulates Xenobiotic Detoxification

    The Nuclear Pregnane X Receptor Regulates Xenobiotic Detoxification di Steven A. Kliewer

    Pubblicazione 2003
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  10. 10
    The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways

    The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways di Claire L. Mellor, Fabian P. Steinmetz, Mark T.D. Cronin

    Pubblicazione 2015
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  11. 11
    CAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α

    CAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α di Jie Gao, Jiong Yan, Meishu Xu, Songrong Ren, Wen Xie

    Pubblicazione 2015
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  12. 12
    Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling

    Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling di Shingo Mutoh, Mack Sobhany, Rick Moore, L. Perera, L. G. Pedersen, Tatsuya Sueyoshi, Masahiko Negishi

    Pubblicazione 2013
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  13. 13
    Human Bile Salt Export Pump Promoter Is Transactivated by the Farnesoid X Receptor/Bile Acid Receptor

    Human Bile Salt Export Pump Promoter Is Transactivated by the Farnesoid X Receptor/Bile Acid Receptor di M Ananthanarayanan, Niranjan Balasubramanian, Makoto Makishima, David J. Mangelsdorf, Frederick J. Suchy

    Pubblicazione 2001
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  14. 14
    Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites

    Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites di Junichiro Sonoda, Ling-Wa Chong, Michael Downes, Grant D. Barish, Sally Coulter, Christopher Liddle, Chih‐Hao Lee, Ronald M. Evans

    Pubblicazione 2005
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  15. 15
    A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response

    A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response di Nico Scheer, Jillian Ross, Anja Rode, Branko Zevnik, Niehaves Sandra, Nicole Faust, C. Roland Wolf

    Pubblicazione 2008
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  16. 16
    Orphan Nuclear Receptors: From Gene to Function*

    Orphan Nuclear Receptors: From Gene to Function* di Vincent Giguère

    Pubblicazione 1999
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  17. 17
    Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

    Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Recep... di Linhao Li, Joseph D. Stanton, Antonia H. Tolson, Yuan Luo, Hongbing Wang

    Pubblicazione 2008
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  18. 18
    Characterization of Peroxisome Proliferator–Activated Receptor α—Independent Effects of PPARα Activators in the Rodent Liver: Di-(2-ethylhexyl) phthalate also Activates the Constitutive-Activated Receptor

    Characterization of Peroxisome Proliferator–Activated Receptor α—Independent Effects of PPARα Activators in the Rodent Liver: Di-(2-ethylhexyl) phthalate also Activates the Constit... di Hongzu Ren, Lauren M. Aleksunes, Carmen R. Wood, Beena Vallanat, Michael H. George, Curtis D. Klaassen, J. Christopher Corton

    Pubblicazione 2009
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  19. 19
    Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice

    Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice di S. P. S. Saini, Ying Mu, Haibiao Gong, David Toma, Hirdesh Uppal, Songrong Ren, Li Song, Samuel M. Poloyac, Wen Xie

    Pubblicazione 2005
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  20. 20
    Med1 Subunit of the Mediator Complex in Nuclear Receptor-Regulated Energy Metabolism, Liver Regeneration, and Hepatocarcinogenesis

    Med1 Subunit of the Mediator Complex in Nuclear Receptor-Regulated Energy Metabolism, Liver Regeneration, and Hepatocarcinogenesis di Yuzhi Jia, Navin Viswakarma, Janardan K. Reddy

    Pubblicazione 2014
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