Resultados da pesquisa

Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1 Por Michael B. Lazarus, Kevan M. Shokat

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Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells Por Huimei Wu, Zi‐Feng Jiang, Peishan Ding, Lijie Shao, Rong‐Yu Liu

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Monitoring Mitophagy in Neuronal Cell Cultures Por Jianhui Zhu, Ruben K. Dagda, Charleen T. Chu

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MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation Por Remi-Martin Laberge, Yu Sun, Arturo V. Orjalo, Christopher K. Patil, Adam Freund, Lili Zhou, S.C. Curran, Albert R. Davalos, Kathleen A. Wilson-Edell, Su Liu, Chandani Limbad, Marco Demaria, Patrick Li, Gene B. Hubbard, Yuji Ikeno, Martin A. Javors, Pierre-Yves Desprez, Christopher C. Benz, Pankaj Kapahi, Peter S. Nelson, Judith Campisi

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E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1 Por Kun Wang, Lu‐Yu Zhou, Jianxun Wang, Yin Wang, Teng Sun, Bing Zhao, Yong-Jie Yang, Tao An, Bo Long, Na Li, Cui-Yun Liu, Ying Gong, Jin-Ning Gao, Yanhan Dong, Jian Zhang, Peifeng Li

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Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate Por Z Liu, Yifei Lv, Na Zhao, G Guan, J Wang

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Tissue-specific autophagy responses to aging and stress in C. elegans Por Hannah C. Chapin, Megan Okada, Alexey J. Merz, Dana L. Miller

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ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts Por Michele N. Washington, Grace Suh, Aaron Orozco, Margie N. Sutton, Hailing Yang, Yu Wang, Weiqun Mao, Steven W. Millward, Argentina Ornelas, N. Atkinson, Warren S.‐L. Liao, Robert C. Bast, Zhen Lü

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Cocaine-Mediated Autophagy in Astrocytes Involves Sigma 1 Receptor, PI3K, mTOR, Atg5/7, Beclin-1 and Induces Type II Programed Cell Death Por Lu Cao, Mary P. Walker, Naveen K. Vaidya, Mingui Fu, Santosh Kumar, Anil Kumar

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Role of autophagy in the pathogenesis of amyotrophic lateral sclerosis Por Jong‐Dae Lee, Jin Hee Shin, Ji Eun Lee, Eui‐Ju Choi

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Molecular network of neuronal autophagy in the pathophysiology and treatment of depression Por Jack Jia, Weidong Le

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Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity Por Judy C. Triplett, Antonella Tramutola, Aaron M. Swomley, Jessime Kirk, Kelly M. Grimes, Kaitilyn N. Lewis, Miranda E. Orr, Karl A. Rodriguez, Jian Cai, Jon B. Klein, Marzia Perluigi, Rochelle Buffenstein, D. Allan Butterfield

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Autophagy in mammalian cells Por Kadija Abounit, Tiziano M. Scarabelli, Roy McCauley

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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A Por Pui‐Mun Wong, Yan Feng, Junru Wang, Rong Shi, Xuejun Jiang

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Cross-talk between bile acids and intestinal microbiota in host metabolism and health Por Yangfan Nie, Jun Hu, Xianghua Yan

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PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes Por Dieter A. Kubli, Melissa Q. Cortez, Alexandra G Moyzis, Rita H. Najor, Youngil Lee, Åsa B. Gustafsson

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HDAC6 inhibition induces mitochondrial fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons Por Pedro Guedes-Dias, João de Proença, Tânia R. Soares, Ana Leitão-Rocha, Brígida R. Pinho, Michael R. Duchen, Jorge M.A. Oliveira

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Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways Por Bo-Syong Pan, Yang-Kao Wang, Meng-Shao Lai, Yi-Fen Mu, Bu‐Miin Huang

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Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy Por Chongshan Dai, Shusheng Tang, Tony Velkov, Xilong Xiao

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Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma Por Andrew R. Stothert, Sarah N. Fontaine, Jonathan J. Sabbagh, Chad A. Dickey

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