Resultados da pesquisa

Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) Por Shyh‐Ming Yang, Adam Yasgar, Bettina Miller, Madhu Lal‐Nag, Kyle R. Brimacombe, Xin Hu, Hongmao Sun, Amy Wang, Xin Xu, Kimloan Nguyen, Udo Oppermann, Marc Ferrer, Vasilis Vasiliou, Anton Simeonov, Ajit Jadhav, David J. Maloney

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Aldehyde dehydrogenase-2 protects against myocardial infarction-related cardiac fibrosis through modulation of the Wnt/β-catenin signaling pathway Por Yingchun Zhou, Xinjun Zhao, Yue Hua, Hongmei Chen, Haiyu Yang, Zhang Tao, Guiqiong Huang, Huijie Fan, Zhang‐Bin Tan, Xiaofang Huang, Bin Liu

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Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824 Por Ramesh V. Nair, George N. Bennett, Eleftherios T. Papoutsakis

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Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase. Por Jaume Farrés, Xiaodong Wang, Koichi Takahashi, Suzanne J. Cunningham, T. T. Wang, Henry Weiner

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The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles Por Bernd Mayer, Matteo Beretta

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Genetic Determinants of Ethanol-Induced Liver Damage Por Adriana Monzoni, Flora Masutti, Gioconda Saccoccio, Stefano Bellentani, Claudio Tiribelli, Mauro Giacca

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Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma Por Shinya Ohashi, Shin’ichi Miyamoto, Osamu Kikuchi, Tomoyuki Gotō, Yusuke Amanuma, Manabu Muto

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Molecular Cloning, Characterization, and Potential Roles of Cytosolic and Mitochondrial Aldehyde Dehydrogenases in Ethanol Metabolism in <i>Saccharomyces cerevisiae</i> Por Xinping Wang, Craig J. Mann, Yinlin Bai, Li Ni, Henry Weiner

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Tissue-distribution of aldehyde dehydrogenase 2 and effects of the Aldh2 gene-disruption on the expression of enzymes involved in alcohol metabolism Por Tsunehiro Oyama

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Acetaldehyde and gastric cancer Por Mikko Salaspuro

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ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis Por Shengfang Jin, Jiang Chen, Lizao Chen, Gavin Histen, Zhi‐Zhong Lin, Stefan Größ, Jeffrey Hixon, Yue Chen, Charles Kung, Yiwei Chen, Yufei Fu, Yuxuan Lu, Hui Lin, Xiujun Cai, Hua Yang, Rob A. Cairns, Marion Dorsch, Shinsan M. Su, Scott A. Biller, Tak W. Mak, Yong Cang

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Alkynol natural products target ALDH2 in cancer cells by irreversible binding to the active site Por Wolfgang Heydenreuter, Elena Kunold, Stephan A. Sieber

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Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant. Por David W. Crabb, Howard J. Edenberg, William Bosron, Tsai‐Kun Li

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Aldehyde dehydrogenase from human liver Por J Hempel, Hedvig von Bahr‐Lindström, Hans Jörnvall

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High incidence of ADH2*1/ALDH2*1 genes among Japanese alcohol dependents and patients with alcoholic liver disease Por F. Tanaka

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Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases Por Stanley A. Moore, Heather M. Baker, Treena J. Blythe, Kathryn E. Kitson, Trevor M. Kitson, Edward N. Baker

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Disruption of the Coenzyme Binding Site and Dimer Interface Revealed in the Crystal Structure of Mitochondrial Aldehyde Dehydrogenase “Asian” Variant Por Heather N. Larson, Henry Weiner, Thomas D. Hurley

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Aldehyde dehydrogenases and cell proliferation Por Giuliana Muzio, M. Maggiora, E. Paiuzzi, Manuela Oraldi, R.A. Canuto

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Characterization of Aldh2 -/- mice as an age-related model of cognitive impairment and Alzheimer’s disease Por Yohan D’Souza, Ahmed Elharram, Raquel Soon-Shiong, R. David Andrew, Brian M. Bennett

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Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation o... Por Alexander Kollau, Alexandra Hofer, Michael Russwurm, Doris Koesling, Wing Ming Keung, Kurt Schmidt, Friedrich Brünner, Bernd Mayer

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