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Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer por Prabhakar Rajan, Jacqueline Stockley, Ian Sudbery, Janis Fleming, Ann Hedley, Gabriela Kalna, David Sims, Chris P. Ponting, Andreas Heger, Craig Robson, R. McMenemin, Ian Pedley, Hing Y. Leung

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Identification of <i>TDRD1</i> as a direct target gene of <i>ERG</i> in primary prostate cancer por Joost L. Boormans, Hanneke Korsten, Angelique J.C. Ziel‐van der Made, Geert J.L.H. van Leenders, Carola V. de Vos, Guido Jenster, Jan Trapman

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N-myc Downstream Regulated Gene 1 (NDRG1) Is Fused to ERG in Prostate Cancer por Dorothee Pflueger, David S. Rickman, Andrea Sboner, Sven Perner, Christopher J. Lafargue, Maria A. Svensson, B.J. Moss, Naoki Kitabayashi, Yihang Pan, Alexandre de la Taille, Rainer Kuefer, Ashutosh Tewari, Francesca Demichelis, Mark S. Chee, Mark Gerstein, Mark A. Rubin

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Nucleotide resolution analysis of <i><scp>TMPRSS2</scp></i> and <i><scp>ERG</scp></i> rearrangements in prostate cancer por Christopher Weier, Michael C. Haffner, Timothy L. Mosbruger, David Esopi, Jessica Hicks, Qizhi Zheng, Helen Fedor, William B. Isaacs, Angelo M. De Marzo, William G. Nelson, Srinivasan Yegnasubramanian

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Urine TMPRSS2:ERG Plus PCA3 for Individualized Prostate Cancer Risk Assessment por Scott A. Tomlins, John Day, Robert J. Lonigro, Daniel H. Hovelson, Javed Siddiqui, Lakshmi P. Kunju, Rodney L. Dunn, Sarah Meyer, Petrea Hodge, Jack Groskopf, John T. Wei, Arul M. Chinnaiyan

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SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression por Wenjian Gan, Xiangpeng Dai, Andrea Lunardi, Zhen Li, Hiroyuki Inuzuka, Pengda Liu, Shoreh Varmeh, Jinfang Zhang, Liang Cheng, Yin Sun, John M. Asara, Andrew H. Beck, Jiaoti Huang, Pier Paolo Pandolfi, Wenyi Wei

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Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration‐resistant prostate cancer por Javier Guerrero, Iván E. Alfaro, Francisco Javier Gómez, Andrew A. Protter, Sebastián Bernales

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Androgen-Induced TMPRSS2 Activates Matriptase and Promotes Extracellular Matrix Degradation, Prostate Cancer Cell Invasion, Tumor Growth, and Metastasis por Chun‐Jung Ko, Cheng-Chung Huang, Hsin-Ying Lin, Chun-Pai Juan, Shaowei Lan, Hsin‐Yi Shyu, Shang‐Ru Wu, Pei‐Wen Hsiao, Hsiang‐Po Huang, Chia‐Tung Shun, Ming‐Shyue Lee

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Molecular Subtyping of Primary Prostate Cancer Reveals Specific and Shared Target Genes of Different ETS Rearrangements por Paula Paulo, Franclim R. Ribeiro, Joana Santos, Diana Mesquita, Mafalda Almeida, João D. Barros‐Silva, Harri M. Itkonen, Rui Henrique, Cármen Jerónimo, Anita Sveen, Ian G. Mills, Rolf I. Skotheim, Ragnhild A. Lothe, Manuel R. Teixeira

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Frequent down-regulation of ABC transporter genes in prostate cancer por Rita Demidenko, Deividas Razanauskas, Kristina Daniūnaitė, Juozas Rimantas Lazutka, Feliksas Jankevičius, Sonata Jarmalaitė

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Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation por Jian An, Shancheng Ren, Stephen J. Murphy, Sumiya Dalangood, Cunjie Chang, Xiaodong Pang, Yangyan Cui, Liguo Wang, Yunqian Pan, Xiaowei Zhang, Yasheng Zhu, Chenji Wang, Geoffrey C. Halling, Liang Cheng, William R. Sukov, R. Jeffrey Karnes, George Vasmatzis, Qing Zhang, Jun Zhang, John C. Cheville, Jun Yan, Yinghao Sun, Haojie Huang

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Regional biases in mutation screening due to intratumoural heterogeneity of prostate cancer por Tae‐Min Kim, Seung‐Hyun Jung, I.-W. Baek, Sung‐Hak Lee, Youn‐Jin Choi, J.W. Lee, Yeun‐Jun Chung, Sug‐Hyung Lee

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Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer por Kyung Park, Scott A. Tomlins, Kumaran Mudaliar, Ya-Lin Chiu, Raquel Esgueva, Rohit Mehra, Khalid Suleman, Sooryanarayana Varambally, J. Chad Brenner, Theresa Y. MacDonald, Abhishek Srivastava, Ashutosh Tewari, Ubaradka G. Sathyanarayana, Dea Nagy, Gary A. Pestano, Lakshmi P. Kunju, Francesca Demichelis, Arul M. Chinnaiyan, Mark A. Rubin

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Epigenomic Alterations in Localized and Advanced Prostate Cancer por Pei‐Chun Lin, Ευγενία Γιαννοπούλου, Kyung Park, Juan Miguel Mosquera, Andrea Sboner, Ashutosh Tewari, Levi A. Garraway, Himisha Beltran, Mark A. Rubin, Olivier Elemento

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Overexpression of thymidylate synthase (TYMS) is associated with aggressive tumor features and early PSA recurrence in prostate cancer por Christoph Burdelski, Christian Strauß, Maria Christina Tsourlakis, Martina Kluth, Claudia Hube‐Magg, Nathaniel Melling, Patrick Lebok, Sarah Minner, Christina Koop, Markus Graefen, Hans Heinzer, Corinna Wittmer, Till Krech, Guido Sauter, Waldemar Wilczak, Ronald Simon, Thorsten Schlomm, Stefan Steurer

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miR-145 suppress the androgen receptor in prostate cancer cells and correlates to prostate cancer prognosis por Olivia Larne, Zandra Hagman, Hans Lilja, Anders Bjartell, Anders Edsjö, Yvonne Ceder

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Fusion in the ETS gene family and prostate cancer por Steven A. Narod, Arun Seth, R. Nam

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A Fluorescence <i>In situ</i> Hybridization Screen for E26 Transformation–Specific Aberrations: Identification of DDX5-ETV4 Fusion Protein in Prostate Cancer por Bo Han, Rohit Mehra, Saravana M. Dhanasekaran, Jindan Yu, Anjana Menon, Robert J. Lonigro, Xiaosong Wang, Yusong Gong, Lei Wang, Sunita Shankar, Bharathi Laxman, Rajal B. Shah, Sooryanarayana Varambally, Nallasivam Palanisamy, Scott A. Tomlins, Chandan Kumar‐Sinha, Arul M. Chinnaiyan

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ERG Rearrangement Metastasis Patterns in Locally Advanced Prostate Cancer por Sven Perner, Maria A. Svensson, Ruhella R. Hossain, John Day, Jack Groskopf, Ryan C. Slaughter, Analee R. Jarleborn, Matthias D. Hofer, Rainer Kuefer, Francesca Demichelis, David S. Rickman, Mark A. Rubin

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TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation por Zineb Mounir, Fallon Lin, Virginia Lin, Joshua M. Korn, Yi Yu, Ricardo A. Valdez, Olulanu H. Aina, Gilles Buchwalter, Aron B. Jaffe, Manav Korpal, Ping Zhu, Myles Brown, Robert D. Cardiff, Jennifer L. Rocnik, Yinhui Yang, Raymond Pagliarini

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