Rezultaty

BRD4 Structure–Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536 od Lijia Chen, Jeremy L. Yap, Makoto Yoshioka, Maryanna E. Lanning, Rachel N. Fountain, Mithun Raje, Jacob A. Scheenstra, Jeffrey Strovel, Steven Fletcher

Dokumenty pełnotekstowe

Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation od Anil Kumar Shukla, Dong Kong, Meena Sharma, Valentin Magidson, Jadranka Lončarek

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Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma od Christian Posch, Brian D. Cholewa, Igor Vujic, Martina Sanlorenzo, Jeffrey Ma, Sarasa T. Kim, Sonja Kleffel, Tobias Schatton, Klemens Rappersberger, Rosie Elizabeth Ann Gutteridge, Nihal Ahmad, Susana Ortiz‐Urda

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Initial testing (stage 1) of the polo‐like kinase inhibitor volasertib (BI 6727), by the Pediatric Preclinical Testing Program od Richard Görlick, E. Anders Kolb, Stephen T. Keir, John M. Maris, C. Patrick Reynolds, Min H. Kang, Hernán Carol, Richard B. Lock, Catherine A. Billups, Raushan T. Kurmasheva, Peter J. Houghton, Malcolm A. Smith

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Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells od Conrad von Schubert, Fabien Cubizolles, Jasmine M. Bracher, Tale Sliedrecht, Geert J.P.L. Kops, Erich A. Nigg

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Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1 od Ewan M. Smith, Nadia Hégarat, Clare Vesely, Isaac Roseboom, Christopher P. Larch, Hansjörg Streicher, Kees R. Straatman, Helen R. Flynn, Mark Skehel, Toru Hirota, Ryoko Kuriyama, Helfrid Hochegger

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Polo-like kinase 1 expression is a prognostic factor in human colon cancer od Wilko Weichert

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Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment od Xiaoqi Liu

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Spatial Separation of Plk1 Phosphorylation and Activity od Wytse Bruinsma, Melinda Aprelia, Jolanda Kool, Libor Macůrek, Arne Lindqvist, René H. Medema

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CAND1 Promotes PLK4-Mediated Centriole Overduplication and Is Frequently Disrupted in Prostate Cancer od Nina Korzeniewski, Markus Hohenfellner, Stefan Duensing

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Recent Advances and New Strategies in Targeting Plk1 for Anticancer Therapy od Kyung S. Lee, Terrence R. Burke, Jung‐Eun Park, Jeong Kyu Bang, Eun Hye Lee

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The mitotic roles of Polo-like kinase od Mary Donaldson, Álvaro A. Tavares, Iain Hagan, Erich A. Nigg, David M. Glover

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KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes od Lingling Duan, Ganesha Rai, Carlos M. Roggero, Qing-Jun Zhang, Qun Wei, Hong Shi, Yunyun Zhou, John Santoyo, Elisabeth D. Martínez, Guanghua Xiao, Ganesh V. Raj, Ajit Jadhav, Anton Simeonov, David J. Maloney, Josep Rizo, Jer‐Tsong Hsieh, Zhiping Liu

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The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles od Thibault Mayor, Ulrike Hacker, York‐Dieter Stierhof, Erich A. Nigg

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Mitotic Transcription Installs Sgo1 at Centromeres to Coordinate Chromosome Segregation od Hong Liu, Qianhui Qu, Ross Warrington, Allyson M. Rice, Ningyan Cheng, Hongtao Yu

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Mitotic Effects of a Constitutively Active Mutant of the <i>Xenopus</i> Polo-Like Kinase Plx1 od Yuewei Qian, E Erikson, James L. Maller

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Checkpoint Genes Required To Delay Cell Division in Response to Nocodazole Respond to Impaired Kinetochore Function in the Yeast <i>Saccharomyces cerevisiae</i> od Yanchang Wang, Daniel J. Burke

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Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1 od Seung Baek Lee, Jung Jin Kim, Hyun-Ja Nam, Bowen Gao, Ping Yin, Bo Qin, Sang Yeop Yi, Hyoungjun Ham, Debra L. Evans, Sun‐Hyun Kim, Jun Zhang, Min Deng, Tongzheng Liu, Haoxing Zhang, Daniel D. Billadeau, Liewei Wang, Emilie Giaime, Jie Shen, Yuan‐Ping Pang, Jin Jen, Jan M. van Deursen, Zhenkun Lou

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The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis od Lisa M. Frenz, Sarah E. Lee, Didier Fesquet, Leland H. Johnston

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Reduced Efficacy of the Plk1 Inhibitor BI 2536 on the Progression of Hepatocellular Carcinoma due to Low Intratumoral Drug Levels od Jörg Haupenthal, Verena Bihrer, Hüdayi Korkusuz, Otto Kollmar, Christian Schmithals, Susanne Kriener, Knut Engels, Thomas Pleli, Alexander Benz, Marta Cañamero, Thomas Longerich, Bernd Kronenberger, Swantje Richter, Oliver Waidmann, Thomas J. Vogl, Stefan Zeuzem, Albrecht Piiper

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