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The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales по Gur Yaari, Jennifer I. C. Benichou, Jason A. Vander Heiden, Steven H. Kleinstein, Yoram Louzoun

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Induction of HIV-1 Broad Neutralizing Antibodies in 2F5 Knock-in Mice: Selection against Membrane Proximal External Region–Associated Autoreactivity Limits T-Dependent Responses по Laurent Verkoczy, Chen Yao, Jinsong Zhang, Hilary Bouton-Verville, Amanda Newman, Bradley Lockwood, Richard M. Scearce, David C. Montefiori, S. Moses Dennison, Shi-Mao Xia, Kwan-Ki Hwang, Hua‐Xin Liao, S. Munir Alam, Barton F. Haynes

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The effect of cell subset isolation method on gene expression in leukocytes по Nadejda Beliakova‐Bethell, Marta Massanella, Cory White, Steven M. Lada, Pinyi Du, Florin Vaida, Julià Blanco, Celsa A. Spina, Christopher H. Woelk

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Germline-encoded amino acids in the αβ T-cell receptor control thymic selection по James Scott‐Browne, Janice White, John W. Kappler, Laurent Gapin, Philippa Marrack

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Two signals are required for negative selection of CD4+CD8+ thymocytes. по Dawne M. Page, Larry Kane, James P. Allison, Stephen Μ. Hedrick

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Thymocytes between the β-Selection and Positive Selection Checkpoints Are Nonresponsive to IL-7 as Assessed by STAT-5 Phosphorylation по C. Justin Van De Wiele, Julie H. Marino, Bryce W. Murray, Stephen S. Vo, Michael Whetsell, T. Kent Teague

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Identifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichment по Agata Levay, Randall Brenneman, Jan Hoinka, David Sant, Marco Cardone, Giorgio Trinchieri, Teresa M. Przytycka, Alexey Berezhnoy

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Evolution and Survival of Marine Carnivores Did Not Require a Diversity of Killer Cell Ig-Like Receptors or Ly49 NK Cell Receptors по John A. Hammond, Lisbeth A. Guethlein, Laurent Abi-Rached, Achim K. Moesta, Peter Parham

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B Cell Selection and Susceptibility to Autoimmunity по Christine Grimaldi, Ruthmarie Hicks, Betty Diamond

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Selection of Cell Populations in Induction of Tolerance: Affinity of Antibody Formed in Partially Tolerant Rabbits по Gail A. Theis, Gregory W. Siskind

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Contingency and entrenchment in protein evolution under purifying selection по Premal Shah, David M. McCandlish, Joshua B. Plotkin

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Space, Selection, and Surveillance: Setting Boundaries with BLyS по Juli P. Miller, Jason Stadanlick, Michael P. Cancro

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Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes по Hui Huang, Eitan Winter, Huajun Wang, Keith G. Weinstock, Heming Xing, Leo Goodstadt, Peter D. Stenson, D.N. Cooper, Andrew R. Smith, M. Mar Albà, Chris P. Ponting, Kim Fechtel

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PREDICTABILITY AND IRREVERSIBILITY OF GENETIC CHANGES ASSOCIATED WITH FLOWER COLOR EVOLUTION IN<i>PENSTEMON BARBATUS</i> по Carolyn A. Wessinger, Mark D. Rausher

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The Fourth Way? Harnessing Aggressive Tendencies in the Thymus по Troy A. Baldwin, Kristin A. Hogquist, Stephen C. Jameson

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Thymus-Blood Protein Interactions Are Highly Effective in Negative Selection and Regulatory T Cell Induction по Danielle F. Atibalentja, Craig A. Byersdorfer, Emil R. Unanue

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Molecular evolution of animal antimicrobial peptides: widespread moderate positive selection по Jacob A. Tennessen

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Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes по Anna Ferrer-Admetlla, Elena Bosch, Martin Sikora, Tomàs Marquès‐Bonet, Anna Ramírez-Soriano, Aura Muntasell, Arcadi Navarro, Ross Lazarus, Francesc Calafell, Jaume Bertranpetit, Ferrán Casals

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Selective pressures on the olfactory receptor repertoire since the human-chimpanzee divergence по Alexander A. Gimelbrant, Helen Skaletsky, Andrew Chess

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CD27/CFSE-Based Ex Vivo Selection of Highly Suppressive Alloantigen-Specific Human Regulatory T Cells по Hans J. P. M. Koenen, Esther Fasse, Irma Joosten

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