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  1. 1
    The Purification and Properties of Pig Liver Geranyl Pyrophosphate Synthetase

    The Purification and Properties of Pig Liver Geranyl Pyrophosphate Synthetase di Jill Dorsey, Judith A. Dorsey, John W. Porter

    Pubblicazione 1966
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  2. 2
    Purification of a mammalian protein geranylgeranyltransferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex.

    Purification of a mammalian protein geranylgeranyltransferase. Formation and catalytic properties of an enzyme-geranylgeranyl pyrophosphate complex. di Kohei Yokoyama, Michael H. Gelb

    Pubblicazione 1993
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  3. 3
    Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester.

    Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coe... di Douglas J. Wilkin, S.Y. Kutsunai, Peter A. Edwards

    Pubblicazione 1990
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  4. 4
    Solubilization and characterization of the long chain prenyltransferase involved in dolichyl phosphate biosynthesis.

    Solubilization and characterization of the long chain prenyltransferase involved in dolichyl phosphate biosynthesis. di W. Lee Adair, Nancy Cafmeyer, R. Kennedy Keller

    Pubblicazione 1984
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  5. 5
    Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants

    Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants di Chengyuan Wang, Qingwen Chen, Dongjie Fan, Jianxu Li, Guodong Wang, Peng Zhang

    Pubblicazione 2015
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  6. 6
    Simvastatin Modulates Cytokine-Mediated Endothelial Cell Adhesion Molecule Induction: Involvement of an Inhibitory G Protein

    Simvastatin Modulates Cytokine-Mediated Endothelial Cell Adhesion Molecule Induction: Involvement of an Inhibitory G Protein di Mehran M. Sadeghi, Mark Collinge, Ruggero Pardi, Jeffrey R. Bender

    Pubblicazione 2000
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  7. 7
    Increased Carotenoid Production by the Food Yeast <i>Candida utilis</i> through Metabolic Engineering of the Isoprenoid Pathway

    Increased Carotenoid Production by the Food Yeast <i>Candida utilis</i> through Metabolic Engineering of the Isoprenoid Pathway di Hiroshi Shimada, Keiji Kondô, Paul D. Fraser, Yutaka Miura, Toshiko Saito, Norihiko Misawa

    Pubblicazione 1998
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  8. 8
    Properties of Kaurene Synthetase from <i>Marah macrocarpus</i> Endosperm: Evidence for the Participation of Separate but Interacting Enzymes

    Properties of Kaurene Synthetase from <i>Marah macrocarpus</i> Endosperm: Evidence for the Participation of Separate but Interacting Enzymes di John D. Duncan, Charles A. West

    Pubblicazione 1981
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  9. 9
    3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy

    3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications... di Farhad R. Danesh, Mehran M. Sadeghi, Nail Amro, Carrie L. Philips, Lixia Zeng, Lin Sun, Atul Sahai, Yashpal S. Kanwar

    Pubblicazione 2002
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  10. 10
    Regulation of Rac1 by Simvastatin in Endothelial Cells

    Regulation of Rac1 by Simvastatin in Endothelial Cells di Ruqin Kou, Juliano L. Sartoretto, Thomas Michel

    Pubblicazione 2009
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  11. 11
    Active isoprenoid pathway in the intra-erythrocytic stages of <i>Plasmodium falciparum</i>: presence of dolichols of 11 and 12 isoprene units

    Active isoprenoid pathway in the intra-erythrocytic stages of <i>Plasmodium falciparum</i>: presence of dolichols of 11 and 12 isoprene units di Alicia S. Couto, Emı́lia A. Kimura, Valnice J. Peres, Marı́a Laura Uhrig, Alejandro M. Katzin

    Pubblicazione 1999
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  12. 12
    Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation <i>in vitro</i>

    Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation <i>... di John Fisher, Michael J. Rogers, J. M. Halasy, Steven P. Luckman, D.E. Hughes, P. Masarachia, Gregg Wesolowski, R.G.G. Russell, Gideon A. Rodan, A A Reszka

    Pubblicazione 1999
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  13. 13
    Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation

    Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation di Na Xu, Ning Shen, Xiuxing Wang, Shan Jiang, Bin Xue, Chaojun Li

    Pubblicazione 2015
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  14. 14
    A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.

    A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity. di Kohei Yokoyama, Gary W. Goodwin, Farideh Ghomashchi, John A. Glomset, Michael H. Gelb

    Pubblicazione 1991
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  15. 15
    Statin effects beyond lipid lowering—are they clinically relevant?

    Statin effects beyond lipid lowering—are they clinically relevant? di Piero O. Bonetti

    Pubblicazione 2003
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  16. 16
    Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast

    Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast di Renee M. Garza, Peter N. Tran, Randolph Y. Hampton

    Pubblicazione 2009
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  17. 17
    Regulation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Degradation by the Nonsterol Mevalonate Metabolite Farnesol in Vivo

    Regulation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Degradation by the Nonsterol Mevalonate Metabolite Farnesol in Vivo di Thomas E. Meigs, Daniel S. Roseman, Robert Simoni

    Pubblicazione 1996
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  18. 18
    Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans

    Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans di Catarina Mörck, Louise C. B. Olsen, Caroline Kurth, Annelie Persson, Nadia Storm, Emma Svensson, John-Olov Jansson, Marika Hellqvist, Annika Enejder, Nils J. Færgeman, Marc Pilon

    Pubblicazione 2009
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  19. 19
    3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors Attenuate β-Amyloid-Induced Microglial Inflammatory Responses

    3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitors Attenuate β-Amyloid-Induced Microglial Inflammatory Responses di Andrew Cordle, Gary E. Landreth

    Pubblicazione 2005
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  20. 20
    Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

    Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma di Masashi Yanae, Masanobu Tsubaki, Takao Satou, Tatsuki Itoh, Motohiro Imano, Yuzuru Yamazoe, Shozo Nishida

    Pubblicazione 2011
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