DNA methylation-based classification of malformations of cortical development in the human brain

DNA methylation-based classification of malformations of cortical development in the human brain

Malformations of cortical development (MCD) comprise a broad spectrum of structural brain lesions frequently associated with epilepsy. Disease definition and diagnosis remain challenging and are often prone to arbitrary judgment. Molecular classification of histopathological entities may help ration...

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Main Authors: Jabari, Samir, Kobow, Katja, Pieper, Tom, Hartlieb, Till, Kudernatsch, Manfred, Polster, Tilman, Bien, Christian G., Kalbhenn, Thilo, Simon, Matthias, Hamer, Hajo, Rössler, Karl, Feucht, Martha, Mühlebner, Angelika, Najm, Imad, Peixoto-Santos, José Eduardo, Gil-Nagel, Antonio, Delgado, Rafael Toledano, Aledo-Serrano, Angel, Hou, Yanghao, Coras, Roland, von Deimling, Andreas, Blümcke, Ingmar
Format: Text
Jezik:angleščina
Izdano: Springer Berlin Heidelberg 2021
Teme:
Original Paper
Online dostop:https://pmc.ncbi.nlm.nih.gov/articles/PMC8732912/
https://pubmed.ncbi.nlm.nih.gov/34797422
http://dx.doi.org/10.1007/s00401-021-02386-0
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