DNA methylation-based classification of malformations of cortical development in the human brain

Malformations of cortical development (MCD) comprise a broad spectrum of structural brain lesions frequently associated with epilepsy. Disease definition and diagnosis remain challenging and are often prone to arbitrary judgment. Molecular classification of histopathological entities may help ration...

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Main Authors: Jabari, Samir, Kobow, Katja, Pieper, Tom, Hartlieb, Till, Kudernatsch, Manfred, Polster, Tilman, Bien, Christian G., Kalbhenn, Thilo, Simon, Matthias, Hamer, Hajo, Rössler, Karl, Feucht, Martha, Mühlebner, Angelika, Najm, Imad, Peixoto-Santos, José Eduardo, Gil-Nagel, Antonio, Delgado, Rafael Toledano, Aledo-Serrano, Angel, Hou, Yanghao, Coras, Roland, von Deimling, Andreas, Blümcke, Ingmar
Format: Text
Language:English
Published: Springer Berlin Heidelberg 2021
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC8732912/
https://pubmed.ncbi.nlm.nih.gov/34797422
http://dx.doi.org/10.1007/s00401-021-02386-0
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