DNA methylation-based classification of malformations of cortical development in the human brain

DNA methylation-based classification of malformations of cortical development in the human brain

Malformations of cortical development (MCD) comprise a broad spectrum of structural brain lesions frequently associated with epilepsy. Disease definition and diagnosis remain challenging and are often prone to arbitrary judgment. Molecular classification of histopathological entities may help ration...

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Autors principals: Jabari, Samir, Kobow, Katja, Pieper, Tom, Hartlieb, Till, Kudernatsch, Manfred, Polster, Tilman, Bien, Christian G., Kalbhenn, Thilo, Simon, Matthias, Hamer, Hajo, Rössler, Karl, Feucht, Martha, Mühlebner, Angelika, Najm, Imad, Peixoto-Santos, José Eduardo, Gil-Nagel, Antonio, Delgado, Rafael Toledano, Aledo-Serrano, Angel, Hou, Yanghao, Coras, Roland, von Deimling, Andreas, Blümcke, Ingmar
Format: Text
Idioma:anglès
Publicat: Springer Berlin Heidelberg 2021
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Original Paper
Accés en línia:https://pmc.ncbi.nlm.nih.gov/articles/PMC8732912/
https://pubmed.ncbi.nlm.nih.gov/34797422
http://dx.doi.org/10.1007/s00401-021-02386-0
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