G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases

G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases

We aimed to determine 1) the mechanism(s) that enables glucose-6-phosphate dehydrogenase (G6PD) to regulate serum response factor (SRF)- and myocardin (MYOCD)-driven smooth muscle cell (SMC)-restricted gene expression, a process that aids in the differentiation of SMCs, and 2) whether G6PD-mediated...

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Hlavní autoři: Dhagia, Vidhi, Kitagawa, Atsushi, Jacob, Christina, Zheng, Connie, D’Alessandro, Angelo, Edwards, John G., Rocic, Petra, Gupte, Rakhee, Gupte, Sachin A.
Médium: Text
Jazyk:angličtina
Vydáno: American Physiological Society 2021
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Research Article
On-line přístup:https://pmc.ncbi.nlm.nih.gov/articles/PMC7988761/
https://pubmed.ncbi.nlm.nih.gov/33416454
http://dx.doi.org/10.1152/ajpheart.00488.2020
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Internet

https://pmc.ncbi.nlm.nih.gov/articles/PMC7988761/
https://pubmed.ncbi.nlm.nih.gov/33416454
http://dx.doi.org/10.1152/ajpheart.00488.2020

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