Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair‐deficient colorectal cancer

Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair‐deficient colorectal cancer

BACKGROUND: Caudal‐related homeobox transcription factor 2 (CDX2) is an intestine‐specific transcription factor implicated in tumour differentiation, proliferation, cell adhesion and migration. Negative CDX2 status (CDX2−) is associated with worse prognosis in colorectal cancer and may identify high...

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Main Authors: Ryan, É. J., Creavin, B., Khaw, Y. L., Kelly, M. E., Mohan, H. M., Geraghty, R., Ryan, E. J., Kennelly, R., Hanly, A., Martin, S. T., Fennelly, D., McDermott, R., Gibbons, D., O'Connell, P. R, Sheahan, K., Winter, D. C.
Format: Text
Language:English
Published: John Wiley & Sons, Ltd 2018
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Original Articles
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC6253792/
https://pubmed.ncbi.nlm.nih.gov/30511046
http://dx.doi.org/10.1002/bjs5.91
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https://pmc.ncbi.nlm.nih.gov/articles/PMC6253792/
https://pubmed.ncbi.nlm.nih.gov/30511046
http://dx.doi.org/10.1002/bjs5.91

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