miR-126 contributes to Parkinson disease by dysregulating IGF-1/PI3K signaling: miRNAs and IGF-1 signaling in Parkinson disease

miR-126 contributes to Parkinson disease by dysregulating IGF-1/PI3K signaling: miRNAs and IGF-1 signaling in Parkinson disease

Dopamine (DA) neurons in sporadic Parkinson disease (PD) display dysregulated gene expression networks and signaling pathways that are implicated in PD pathogenesis. Micro (mi)RNAs are regulators of gene expression, which could be involved in neurodegenerative diseases. We determined the miRNA profi...

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Hlavní autoři: Kim, Woori, Lee, Yenarae, McKenna, Noah D., Yi, Ming, Simunovic, Filip, Wang, Yulei, Kong, Benjamin, Rooney, Robert J., Seo, Hyemyung, Stephens, Robert, Sonntag, Kai C.
Médium: Text
Jazyk:angličtina
Vydáno: 2014
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Article
On-line přístup:https://pmc.ncbi.nlm.nih.gov/articles/PMC3991567/
https://pubmed.ncbi.nlm.nih.gov/24559646
http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.021
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https://pmc.ncbi.nlm.nih.gov/articles/PMC3991567/
https://pubmed.ncbi.nlm.nih.gov/24559646
http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.021

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