TD-60 links RalA GTPase function to the CPC in mitosis

Abstract TD-60 (also known as RCC2) is a highly conserved protein that structurally resembles the Ran guanine exchange factor (GEF) RCC1, but has not previously been shown to have GEF activity. TD-60 has a typical chromosomal passenger complex (CPC) distribution in mitotic cells, but associates with...

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Autors principals: Diana Papini, Lars Langemeyer, Maria Alba Abad, Alastair Kerr, Itaru Samejima, Patrick A. Eyers, A. Arockia Jeyaprakash, Jonathan M.G. Higgins, Francis A. Barr, William C. Earnshaw
Format: Artigo
Idioma:anglès
Publicat: 2015
Accés en línia:https://doi.org/10.1038/ncomms8678
https://www.nature.com/articles/ncomms8678.pdf
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