TD-60 links RalA GTPase function to the CPC in mitosis
Abstract TD-60 (also known as RCC2) is a highly conserved protein that structurally resembles the Ran guanine exchange factor (GEF) RCC1, but has not previously been shown to have GEF activity. TD-60 has a typical chromosomal passenger complex (CPC) distribution in mitotic cells, but associates with...
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Main Authors: | Diana Papini, Lars Langemeyer, Maria Alba Abad, Alastair Kerr, Itaru Samejima, Patrick A. Eyers, A. Arockia Jeyaprakash, Jonathan M.G. Higgins, Francis A. Barr, William C. Earnshaw |
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Format: | Artigo |
Language: | English |
Published: |
2015
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Online Access: | https://doi.org/10.1038/ncomms8678 https://www.nature.com/articles/ncomms8678.pdf |
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