ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution

ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution

Abstract Dipeptidyl peptidase-4 (DPP4) is a well-established receptor for several MERS-related coronaviruses (MERSr-CoVs) isolated from humans, camels, pangolins, and bats (1–6). However, the receptor usage of many genetically diverse bat MERSr-CoVs with broad geographical distributions remains poor...

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Main Authors: Chen Liu, Young‐Jun Park, Chengbao Ma, C Stuart, Risako Gen, Yucheng Sun, Xiao Yang, M C Lin, Qing Xiong, Jun-Yu Si, Peng Liu, David Veesler, Huan Yan
Format: Pré-impressão
Language:English
Published: 2025
Online Access:https://doi.org/10.1101/2025.02.19.639017
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https://doi.org/10.1101/2025.02.19.639017

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