ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution

Abstract Dipeptidyl peptidase-4 (DPP4) is a well-established receptor for several MERS-related coronaviruses (MERSr-CoVs) isolated from humans, camels, pangolins, and bats (1–6). However, the receptor usage of many genetically diverse bat MERSr-CoVs with broad geographical distributions remains poor...

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Hlavní autoři: Chen Liu, Young‐Jun Park, Chengbao Ma, C Stuart, Risako Gen, Yucheng Sun, Xiao Yang, M C Lin, Qing Xiong, Jun-Yu Si, Peng Liu, David Veesler, Huan Yan
Médium: Pré-impressão
Jazyk:angličtina
Vydáno: 2025
On-line přístup:https://doi.org/10.1101/2025.02.19.639017
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