Discovery of Mutated Oncodriver Genes associated with Glioblastoma Originated from Stem Cells of Subventricular Zone through the Whole Exome Sequence Profile Analysis, and Drug Repurposing

Discovery of Mutated Oncodriver Genes associated with Glioblastoma Originated from Stem Cells of Subventricular Zone through the Whole Exome Sequence Profile Analysis, and Drug Repurposing

Glioblastoma (GBM) is one of the most aggressive cancers due to its high mortality rate in spite of intensive treatment. It may be happened because of drug resistance against their typical receptors, since these receptor genes are often mutated by environmental stress. So identifying mutated oncodri...

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Hlavní autoři: Arnob Sarker, Burhan Uddin, Reaz Ahmmed, Sabkat Mahmud, Alvira Ajadee, Md. Al Amin Pappu, Md. Abdul Aziz, Md. Nurul Haque Mollah
Médium: Artigo
Jazyk:angličtina
Vydáno: 2025
On-line přístup:https://doi.org/10.1016/j.heliyon.2025.e42052
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https://doi.org/10.1016/j.heliyon.2025.e42052

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