Tumor initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice

Tumor initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice

Tumor-initiating cells (TICs) play a key role in cancer progression and immune escape. However, how TICs evade immune elimination remains poorly characterized. Combining single-cell RNA sequencing (scRNA-seq), dual-recombinase-based lineage tracing, and other approaches, we identified a WNT-activate...

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Hlavní autoři: Shuang Chen, Chen‐Song Huang, Kang Li, Maosheng Cheng, Caihua Zhang, Jianqi Xiong, Guoli Tian, Ruoxing Zhou, Rongsong Ling, Xiaochen Wang, Gan Xiong, Zhihui Zhang, Jieyi Ma, Yan Zhu, Bin Zhou, Liang Peng, Zhenwei Peng, Heping Li, Demeng Chen
Médium: Artigo
Jazyk:angličtina
Vydáno: 2025
On-line přístup:https://doi.org/10.1172/jci180893
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https://doi.org/10.1172/jci180893

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