Helicobacter pylori infection promotes M1 macrophage polarization and gastric inflammation by activation of NLRP3 inflammasome via TNF/TNFR1 axis
Macrophages play a crucial role in chronic gastritis induced by the pathogenic Helicobacter pylori (H. pylori) infection. NLRP3 inflammasome has emerged as an important component of inflammatory processes. However, the molecular mechanism by which H. pylori infection drives NLRP3 inflammasome and ma...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | inglés |
Publicado: |
2025
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Acceso en liña: | https://doi.org/10.1186/s12964-024-02017-7 |
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