Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons

Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons

Neuropathic pain is a debilitating chronic condition that lacks effective treatment. The role of cytokine- and chemokine-mediated neuroinflammation in its pathogenesis has been well documented. Follistatin (FST) is a secreted protein known to antagonize the biological activity of cytokines in the tr...

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Main Authors: Bao‐Chun Jiang, Yuejuan Ling, Menglin Xu, Jun Gu, Xiaobo Wu, Wei‐Lin Sha, Tian Tian, Xue‐Hui Bai, Nan Li, Changyu Jiang, Chen Ouyang, Ling-Jie Ma, Zhijun Zhang, Yibin Qin, Meixuan Zhu, Hong-Jie Yuan, Long‐Jun Wu, Ru‐Rong Ji, Yong‐Jing Gao
格式: Artigo
语言:英语
出版: 2024
在线阅读:https://doi.org/10.1126/scitranslmed.adi1564
https://www.science.org/doi/pdf/10.1126/scitranslmed.adi1564?download=true
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https://doi.org/10.1126/scitranslmed.adi1564
https://www.science.org/doi/pdf/10.1126/scitranslmed.adi1564?download=true

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