Generation of human iPSC-derived 3D bile duct within liver organoid by incorporating human iPSC-derived blood vessel

In fetal development, tissue interaction such as the interplay between blood vessel (BV) and epithelial tissue is crucial for organogenesis. Here we recapitulate the spatial arrangement between liver epithelial tissue and the portal vein to observe the formation of intrahepatic bile ducts (BDs) from...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Erica Carolina, Yoshiki Kuse, Ayumu Okumura, Kenji Aoshima, Tomomi Tadokoro, Shinya Matsumoto, Eriko Kanai, Takashi Okumura, Toshiharu Kasai, S. Yamabe, Yuji Nishikawa, Kiyoshi Yamaguchi, Yoichi Furukawa, Naoki Tanimizu, Hideki Taniguchi
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2024
Urunga tuihono:https://doi.org/10.1038/s41467-024-51487-3
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