Generation of human iPSC-derived 3D bile duct within liver organoid by incorporating human iPSC-derived blood vessel
In fetal development, tissue interaction such as the interplay between blood vessel (BV) and epithelial tissue is crucial for organogenesis. Here we recapitulate the spatial arrangement between liver epithelial tissue and the portal vein to observe the formation of intrahepatic bile ducts (BDs) from...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | inglés |
Publicado: |
2024
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Acceso en liña: | https://doi.org/10.1038/s41467-024-51487-3 |
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