Generation of human iPSC-derived 3D bile duct within liver organoid by incorporating human iPSC-derived blood vessel

Generation of human iPSC-derived 3D bile duct within liver organoid by incorporating human iPSC-derived blood vessel

In fetal development, tissue interaction such as the interplay between blood vessel (BV) and epithelial tissue is crucial for organogenesis. Here we recapitulate the spatial arrangement between liver epithelial tissue and the portal vein to observe the formation of intrahepatic bile ducts (BDs) from...

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Main Authors: Erica Carolina, Yoshiki Kuse, Ayumu Okumura, Kenji Aoshima, Tomomi Tadokoro, Shinya Matsumoto, Eriko Kanai, Takashi Okumura, Toshiharu Kasai, S. Yamabe, Yuji Nishikawa, Kiyoshi Yamaguchi, Yoichi Furukawa, Naoki Tanimizu, Hideki Taniguchi
Format: Artigo
Language:English
Published: 2024
Online Access:https://doi.org/10.1038/s41467-024-51487-3
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https://doi.org/10.1038/s41467-024-51487-3

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