Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II
Blockade of immune checkpoint receptors has shown outstanding efficacy for tumor immunotherapy. Promising treatment with anti-lymphocyte-activation gene-3 (LAG-3) has already been recognized as the next efficacious treatment, but there is still limited understanding of the mechanism of LAG-3-mediate...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
2024
|
| Online Access: | https://doi.org/10.1016/j.celrep.2024.114655 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!