Protective role for kidney TREM2 macrophages in obesity- and diabetes-induced kidney injury

Protective role for kidney TREM2 macrophages in obesity- and diabetes-induced kidney injury

Diabetic kidney disease (DKD), the most common cause of kidney failure, is a frequent complication of diabetes and obesity, and yet to date, treatments to halt its progression are lacking. We analyze kidney single-cell transcriptomic profiles from DKD patients and two DKD mouse models at multiple ti...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ayshwarya Subramanian, Katherine A. Vernon, Yiming Zhou, Jamie L. Marshall, Maria Alimova, Carlos Arevalo, Fan Zhang, Michal Slyper, Julia Waldman, Mónica S. Montesinos, Danielle Dionne, Lan Nguyễn, Michael S. Cuoco, Dan Dubinsky, Jason Q. Purnell, Keith Keller, Samuel H. Sturner, Elizabeth Grinkevich, Ayan Ghoshal, A. Kötek, Giorgio Trivioli, Nathan Richoz, Mary Beth Humphrey, Isabella G. Darby, Sarah J. Miller, Yingping Xu, Astrid Weins, Alexandra Chloe-Villani, Steven L. Chang, Matthias Kretzler, Orit Rosenblatt-Rosen, Jillian L. Shaw, Kurt A. Zimmerman, Menna R. Clatworthy, Aviv Regev, Anna Greka
Médium: Artigo
Jazyk:angličtina
Vydáno: 2024
On-line přístup:https://doi.org/10.1016/j.celrep.2024.114253
https://www.cell.com/article/S2211124724005813/pdf
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Internet

https://doi.org/10.1016/j.celrep.2024.114253
https://www.cell.com/article/S2211124724005813/pdf

Podobné jednotky