Radiotherapy-sensitized cancer immunotherapy via cGAS-STING immune pathway by activatable nanocascade reaction

Radiotherapy-sensitized cancer immunotherapy via cGAS-STING immune pathway by activatable nanocascade reaction

Abstract Radiotherapy-induced immune activation holds great promise for optimizing cancer treatment efficacy. Here, we describe a clinically used radiosensitizer hafnium oxide (HfO 2 ) that was core coated with a MnO 2 shell followed by a glucose oxidase (GOx) doping nanoplatform (HfO 2 @MnO 2 @GOx,...

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Hlavní autoři: Honglei Hu, Shuting Zheng, Chenxi He, Yinfei Zheng, Qiming Wei, Siwen Chen, Zede Wu, Yikai Xu, Bingxia Zhao, Chenggong Yan
Médium: Artigo
Jazyk:angličtina
Vydáno: 2024
On-line přístup:https://doi.org/10.1186/s12951-024-02502-8
https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-024-02502-8
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Internet

https://doi.org/10.1186/s12951-024-02502-8
https://jnanobiotechnology.biomedcentral.com/counter/pdf/10.1186/s12951-024-02502-8

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