Multi-Omics profiling identifies aldehyde dehydrogenase 2 as a critical mediator in the crosstalk between Treg-mediated immunosuppression microenvironment and hepatocellular carcinoma

Dysregulation of the aldehyde dehydrogenase (ALDH) family has been implicated in various pathological conditions, including cancer.However, a systematic evaluation of ALDH alterations and their therapeutic relevance in hepatocellular carcinoma (HCC) remains lacking.Herein, we found that 15 of 19 ALD...

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Main Authors: Zhiyong Liu, Xiahui Lin, Hongying Guo, Xuan Shi, Danying Zhang, Jialei Sun, Guangcong Zhang, Ru-Chen Xu, Fu Wang, Xiang‐Nan Yu, Dou Wang, Shuqiang Weng, Xizhong Shen, Taotao Liu, Ling Dong, Ji‐Min Zhu
格式: Artigo
语言:英语
出版: 2024
在线阅读:https://doi.org/10.7150/ijbs.93075
https://www.ijbs.com/v20p2763.pdf
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