Multiomic analysis reveals developmental dynamics of the human heart in health and disease

Abstract Developmental dynamics encompass both the specification of cell types and their spatial organisation into multicellular niches. Here we harness the power of single-cell and spatial multiomics to unravel embryonic and foetal cardiac tissue niches, which lead to the development of a new tool,...

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Hlavní autoři: James Cranley, Kazumasa Kanemaru, Semih Bayraktar, Vincent Knight-Schrijver, J. Patrick Pett, Krzysztof Polański, Monika Dabrowska, Ilaria Mulas, Laura Richardson, Claudia I. Semprich, Rakeshlal Kapuge, Shani Perera, Xiaoling He, Siew Yen Ho, Nadav Yayon, Elizabeth Tuck, Kenny Roberts, Jack A. Palmer, Hongorzul Davaapil, Laure Gambardella, Minal Patel, Richard Tyser, Sanjay Sinha, Sarah A. Teichmann
Médium: Pré-impressão
Jazyk:angličtina
Vydáno: 2024
On-line přístup:https://doi.org/10.1101/2024.04.29.591736
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