The Role of Fatty Acid Synthase in the Vascular Smooth Muscle Cell to Foam Cell Transition

Vascular smooth muscle cells (VSMCs), in their contractile and differentiated state, are fundamental for maintaining vascular function. Upon exposure to cholesterol (CHO), VSMCs undergo dedifferentiation, adopting characteristics of foam cells—lipid-laden, macrophage-like cells pivotal in atheroscle...

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Hlavní autoři: Bethany J Bogan, Holly C. Williams, Claire M Holden, Vraj Patel, Giji Joseph, Christopher Fierro, Hugo Sepúlveda, W. Robert Taylor, Amir Rezvan, Alejandra San Martín
Médium: Artigo
Jazyk:angličtina
Vydáno: 2024
On-line přístup:https://doi.org/10.3390/cells13080658
https://www.mdpi.com/2073-4409/13/8/658/pdf?version=1712655513
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