Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice

Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice

Heart failure with preserved ejection fraction (HFpEF) poses therapeutic challenges due to the limited treatment options. Building upon our previous research that demonstrates the efficacy of histone deacetylase 6 (HDAC6) inhibition in a genetic cardiomyopathy model, we investigate HDAC6's role...

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Hlavní autoři: Sara Ranjbarvaziri, Aliya Zeng, Iris Wu, Amara Greer-Short, Farshad Farshidfar, Ana Budan, Emma Xu, Reva Shenwai, Matthew Kozubov, Cindy Li, Melissa Van Pell, Francis Grafton, Charles Mackay, Xiaomei Song, James R. Priest, Gretchen Argast, Mohammad A. Mandegar, Timothy Hoey, Jin Yang
Médium: Artigo
Jazyk:angličtina
Vydáno: 2024
On-line přístup:https://doi.org/10.1038/s41467-024-45440-7
https://www.nature.com/articles/s41467-024-45440-7.pdf
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https://doi.org/10.1038/s41467-024-45440-7
https://www.nature.com/articles/s41467-024-45440-7.pdf

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