Regulation of autophagy by perilysosomal calcium: a new player in β-cell lipotoxicity
Autophagy is an essential quality control mechanism for maintaining organellar functions in eukaryotic cells. Defective autophagy in pancreatic beta cells has been shown to be involved in the progression of diabetes through impaired insulin secretion under glucolipotoxic stress. The underlying mecha...
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| Main Authors: | , , , |
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| Format: | Revisão |
| Language: | English |
| Published: |
2024
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| Online Access: | https://doi.org/10.1038/s12276-024-01161-x https://www.nature.com/articles/s12276-024-01161-x.pdf |
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