Limitations of Protein Structure Prediction Algorithms in Therapeutic Protein Development

The three-dimensional protein structure is pivotal in comprehending biological phenomena. It directly governs protein function and hence aids in drug discovery. The development of protein prediction algorithms, such as AlphaFold2, ESMFold, and trRosetta, has given much hope in expediting protein-bas...

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Main Authors: Sarfaraz K. Niazi, Zamara Mariam, Rehan Zafar Paracha
格式: Artigo
语言:英语
出版: 2024
在线阅读:https://doi.org/10.3390/biomedinformatics4010007
https://www.mdpi.com/2673-7426/4/1/7/pdf?version=1704696095
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