A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

SUMMARY Neuroblastoma is a pediatric cancer arising from the developing sympathoadrenal lineage with complex inter- and intra-tumoral heterogeneity. To chart this complexity, we generated a comprehensive cell atlas of 55 neuroblastoma patient tumors, collected from two pediatric cancer institutions,...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Anand G. Patel, Orr Ashenberg, Natalie B. Collins, Åsa Segerstolpe, Sizun Jiang, Michal Slyper, Xin Huang, Chiara Caraccio, Hongjian Jin, Heather Sheppard, Ke Xu, Ti‐Cheng Chang, Brent A. Orr, Abbas Shirinifard, Richard H. Chapple, Amber Shen, Michael R. Clay, Ruth Tatevossian, Colleen Reilly, Jaimin Patel, Marybeth Lupo, Cynthia Cline, Danielle Dionne, Caroline Porter, Julia Waldman, Yunhao Bai, Bokai Zhu, Irving Barrera, Evan Murray, Sébastien Vigneau, Sara Napolitano, Isaac Wakiro, Jingyi Wu, Grace Grimaldi, Laura DelloStritto, Karla Helvie, Asaf Rotem, Ana Lako, Nicole Cullen, Kathleen L. Pfaff, Åsa Karlström, Judit Jané‐Valbuena, Ellen Todres, Aaron R. Thorner, Paul Geeleher, Scott J. Rodig, Xin Zhou, Elizabeth Stewart, Bruce E. Johnson, Gang Wu, Fei Chen, Jiyang Yu, Yury Goltsev, Garry P. Nolan, Orit Rozenblatt–Rosen, Aviv Regev, Michael A. Dyer
التنسيق:	Pré-impressão
اللغة:	الإنجليزية
منشور في:	2024
الوصول للمادة أونلاين:	https://doi.org/10.1101/2024.01.07.574538 https://www.biorxiv.org/content/biorxiv/early/2024/01/16/2024.01.07.574538.full.pdf
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

الانترنت

https://doi.org/10.1101/2024.01.07.574538
https://www.biorxiv.org/content/biorxiv/early/2024/01/16/2024.01.07.574538.full.pdf

A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

الانترنت

مواد مشابهة