N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA

N-acetyltransferase 10 regulates alphavirus replication via N4-acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA

ABSTRACT Epitranscriptomic RNA modifications can regulate the stability of mRNA and affect cellular and viral RNA functions. The N4-acetylcytidine (ac4C) modification in the RNA viral genome was recently found to promote viral replication; however, the mechanism by which RNA acetylation in the host...

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Hlavní autoři: Yamei Dang, Jia Li, Yuchang Li, Yuan Wang, Yajing Zhao, Ningbo Zhao, Wanying Li, Hui Zhang, Chuantao Ye, Hongwei Ma, Liang Zhang, He Liu, Yangchao Dong, Min Yao, Yingfeng Lei, Zhikai Xu, Fanglin Zhang, Wei Ye
Médium: Artigo
Jazyk:angličtina
Vydáno: 2024
On-line přístup:https://doi.org/10.1128/jvi.01350-23
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https://doi.org/10.1128/jvi.01350-23

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