Macrophages reprogramming driven by cancer-associated fibroblasts under FOLFIRINOX treatment correlates with shorter survival in pancreatic cancer

Macrophages reprogramming driven by cancer-associated fibroblasts under FOLFIRINOX treatment correlates with shorter survival in pancreatic cancer

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) remains a clinically challenging cancer, mainly due to limited therapeutic options and the presence of a highly prominent tumor microenvironment (TME), facilitating tumor progression. The TME is predominated by heterogeneous populations of...

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Main Authors: Zainab Hussain, Thomas Bertran, Pascal Finetti, Eugénie Lohmann, Émilie Mamessier, Ghislain Bidaut, François Bertucci, Moacyr Jesus Barreto de Melo Rêgo, Richard Tomasini
Format: Artigo
Language:English
Published: 2024
Online Access:https://doi.org/10.1186/s12964-023-01388-7
https://biosignaling.biomedcentral.com/counter/pdf/10.1186/s12964-023-01388-7
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https://doi.org/10.1186/s12964-023-01388-7
https://biosignaling.biomedcentral.com/counter/pdf/10.1186/s12964-023-01388-7

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